TRIP10

TRIP10
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2CT4, 2EFK, 2KE4
Dynodwyr
Cyfenwau	TRIP10, CIP4, HSTP, STOT, STP, TRIP-10, thyroid hormone receptor interactor 10
Dynodwyr allanol	OMIM: 604504 HomoloGene: 99728 GeneCards: TRIP10
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • identical protein binding • lipid binding • GO:0005097, GO:0005099, GO:0005100 GTPase activator activity Cydrannau o'r gell • cytoplasm • cytosol • Golgi apparatus • cell projection • intracellular membrane-bounded organelle • bilen • Cellbilen • nucleoplasm • cell cortex • perinuclear region of cytoplasm • lysosome • phagocytic cup • Cytosgerbwd • extracellular exosome Prosesau biolegol • endocytosis • cell communication • regulation of small GTPase mediated signal transduction • GO:0072468 signal transduction • GO:0032320, GO:0032321, GO:0032855, GO:0043089, GO:0032854 positive regulation of GTPase activity • actin cytoskeleton organization • membrane organization Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	9322	n/a
Ensembl	ENSG00000125733	n/a
UniProt	Q15642	n/a
RefSeq (mRNA)	NM_001288962 NM_001288963 NM_004240	n/a
RefSeq (protein)	NP_001275891 NP_001275892 NP_004231	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn TRIP10 yw TRIP10 a elwir hefyd yn Thyroid hormone receptor interactor 10 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 19, band 19p13.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn TRIP10.

• STP
• CIP4
• HSTP
• STOT
• TRIP-10

Llyfryddiaeth

• "CIP4 promotes lung adenocarcinoma metastasis and is associated with poor prognosis. ". Oncogene. 2015. PMID 25174397.
• "Cdc42-interacting protein 4 promotes breast cancer cell invasion and formation of invadopodia through activation of N-WASp. ". Cancer Res. 2010. PMID 20940394.
• "CDC42-interacting protein 4 promotes metastasis of nasopharyngeal carcinoma by mediating invadopodia formation and activating EGFR signaling. ". J Exp Clin Cancer Res. 2017. PMID 28129778.
• "CIP4 promotes metastasis in triple-negative breast cancer and is associated with poor patient prognosis. ". Oncotarget. 2015. PMID 25823823.
• "The CDC42-interacting protein 4 controls epithelial cell cohesion and tumor dissemination.". Dev Cell. 2014. PMID 25203208.