TPSAB1

TPSAB1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1A0L, 2BM2, 2FPZ, 2FS8, 2FS9, 2FWW, 2FXR, 2GDD, 2ZA5, 3V7T,%%s1LTO, 2F9N, 2F9O, 2F9P, 2ZEB, 2ZEC, 4A6L, 4MPU, 4MPV, 4MPW, 4MPX, 4MQA, 5F03
Dynodwyr
Cyfenwau	TPSAB1, TPS1, TPS2, TPSB1, tryptase alpha/beta 1, TPSB2, Tryptase-2
Dynodwyr allanol	OMIM: 191080 HomoloGene: 55729 GeneCards: TPSAB1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0070122 peptidase activity • serine-type peptidase activity • GO:0001948, GO:0016582 protein binding • hydrolase activity • serine-type endopeptidase activity • identical protein binding Cydrannau o'r gell • extracellular region • GO:0005578 extracellular matrix • extracellular space • collagen-containing extracellular matrix Prosesau biolegol • proteolysis • defense response • extracellular matrix disassembly Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	7177	n/a
Ensembl	ENSG00000172236	n/a
UniProt	P20231 Q15661	n/a
RefSeq (mRNA)	NM_003294	n/a
RefSeq (protein)	NP_077078 NP_003285	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn TPSAB1 yw TPSAB1 a elwir hefyd yn Tryptase alpha/beta-1 a Tryptase alpha/beta 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 16, band 16p13.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn TPSAB1.

• TPS1
• TPS2
• TPSB1

Llyfryddiaeth

• "Assessment of clinical findings, tryptase levels, and bone marrow histopathology in the management of pediatric mastocytosis. ". J Allergy Clin Immunol. 2015. PMID 26044856.
• "Correlation between serum tryptase, mast cells positive to tryptase and microvascular density in colo-rectal cancer patients: possible biological-clinical significance. ". PLoS One. 2014. PMID 24915568.
• "Diagnostic Value of Serum Baseline Tryptase Levels in Childhood Asthma and Its Correlation with Disease Severity. ". Int Arch Allergy Immunol. 2016. PMID 28049209.
• "Elevated basal serum tryptase identifies a multisystem disorder associated with increased TPSAB1 copy number. ". Nat Genet. 2016. PMID 27749843.
• "Basal serum tryptase is not a risk factor for immediate-type drug hypersensitivity during childhood.". Pediatr Allergy Immunol. 2016. PMID 27288661.