TNFRSF4

TNFRSF4
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1D0A, 2HEV, 2HEY
Dynodwyr
Cyfenwau	TNFRSF4, ACT35, CD134, IMD16, OX40, TXGP1L, tumor necrosis factor receptor superfamily member 4, TNF receptor superfamily member 4
Dynodwyr allanol	OMIM: 600315 HomoloGene: 2496 GeneCards: TNFRSF4
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • virus receptor activity • tumor necrosis factor-activated receptor activity • GO:0001948, GO:0016582 protein binding Cydrannau o'r gell • integral component of membrane • bilen • Cellbilen • integral component of plasma membrane • cell surface • external side of plasma membrane Prosesau biolegol • regulation of apoptotic process • tumor necrosis factor-mediated signaling pathway • negative regulation of DNA-binding transcription factor activity • multicellular organism development • T cell proliferation • response to lipopolysaccharide • regulation of cell population proliferation • positive regulation of B cell proliferation • GO:0046730, GO:0046737, GO:0046738, GO:0046736 immune response • apoptotic signaling pathway • viral entry into host cell • inflammatory response • GO:0045996 negative regulation of transcription, DNA-templated • GO:0022415 viral process • cellular defense response • regulation of protein kinase activity • negative regulation of activation-induced cell death of T cells • negative regulation of extrinsic apoptotic signaling pathway Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	7293	n/a
Ensembl	ENSG00000186827	n/a
UniProt	P43489	n/a
RefSeq (mRNA)	NM_003327	n/a
RefSeq (protein)	NP_003318	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn TNFRSF4 yw TNFRSF4 a elwir hefyd yn TNF receptor superfamily member 4 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 1, band 1p36.33.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn TNFRSF4.

• OX40
• ACT35
• CD134
• IMD16
• TXGP1L

Llyfryddiaeth

• "Preferential expression of CD134, an HHV-6 cellular receptor, on CD4T cells in drug-induced hypersensitivity syndrome (DIHS)/drug reaction with eosinophilia and systemic symptoms (DRESS). ". J Dermatol Sci. 2016. PMID 27174092.
• "Lack of Association Between rs17568 Polymorphism in OX40 Gene and Myocardial Infarction, Southern of Iran. ". Glob J Health Sci. 2015. PMID 26755473.
• "OX40 expression enhances the prognostic significance of CD8 positive lymphocyte infiltration in colorectal cancer. ". Oncotarget. 2015. PMID 26439988.
• "Determinants of Human CD134 Essential for Entry of Human Herpesvirus 6B. ". J Virol. 2015. PMID 26202244.
• "Detailed study of the interaction between human herpesvirus 6B glycoprotein complex and its cellular receptor, human CD134.". J Virol. 2014. PMID 25008928.