TIAL1

TIAL1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1X4G, 2CQI, 2DH7
Dynodwyr
Cyfenwau	TIAL1, TCBP, TIAR, TIA1 cytotoxic granule-associated RNA binding protein-like 1, TIA1 cytotoxic granule associated RNA binding protein like 1
Dynodwyr allanol	OMIM: 603413 HomoloGene: 87796 GeneCards: TIAL1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • nucleic acid binding • RNA binding • DNA binding • mRNA 3'-UTR AU-rich region binding Cydrannau o'r gell • cytoplasm • cytoplasmic stress granule • lysosome • extracellular exosome • cnewyllyn cell • nucleoplasm • ribonucleoprotein complex Prosesau biolegol • GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II • germ cell development • defense response • stem cell division • positive regulation of cell population proliferation • GO:0097285 apoptotic process • fibroblast growth factor receptor signaling pathway Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	7073	n/a
Ensembl	ENSG00000151923	n/a
UniProt	Q01085	n/a
RefSeq (mRNA)	NM_001033925 NM_003252 NM_001323964 NM_001323965 NM_001323967 NM_001323968 NM_001323969 NM_001323970 NM_022333	n/a
RefSeq (protein)	NP_001029097 NP_001310893 NP_001310894 NP_001310896 NP_001310897 NP_001310898 NP_001310899 NP_003243	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn TIAL1 yw TIAL1 a elwir hefyd yn TIA1 cytotoxic granule associated RNA binding protein like 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 10, band 10q26.11.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn TIAL1.

• TCBP
• TIAR

Llyfryddiaeth

• "Novel DNA-binding properties of the RNA-binding protein TIAR. ". Nucleic Acids Res. 2005. PMID 16091628.
• "TIA proteins are necessary but not sufficient for the tissue-specific splicing of the myosin phosphatase targeting subunit 1. ". J Biol Chem. 2004. PMID 14736875.
• "Distinct binding properties of TIAR RRMs and linker region. ". RNA Biol. 2013. PMID 23603827.
• "Elucidation of a C-rich signature motif in target mRNAs of RNA-binding protein TIAR. ". Mol Cell Biol. 2007. PMID 17682065.
• "Translational repression by RNA-binding protein TIAR.". Mol Cell Biol. 2006. PMID 16537914.