SCARB2

SCARB2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 4F7B, 4Q4B, 4Q4F, 4TVZ, 4TW0, 4TW2
Dynodwyr
Cyfenwau	SCARB2, AMRF, CD36L2, EPM4, HLGP85, LGP85, LIMP-2, LIMPII, SR-BII, scavenger receptor class B member 2
Dynodwyr allanol	OMIM: 602257 HomoloGene: 48353 GeneCards: SCARB2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • enzyme binding • GO:0001948, GO:0016582 protein binding • virus receptor activity • phosphatidylserine binding • transmembrane signaling receptor activity • scavenger receptor activity • phospholipid transporter activity • cholesterol binding • phosphatidylcholine binding • protein homodimerization activity • chaperone binding • cargo receptor activity Cydrannau o'r gell • integral component of membrane • lysosome • lysosomal lumen • extracellular exosome • bilen • focal adhesion • lysosomal membrane • Cellbilen • clathrin-coated vesicle membrane • late endosome membrane • Golgi membrane • endoplasmic reticulum membrane • endosome membrane • endocytic vesicle membrane Prosesau biolegol • viral entry into host cell • protein targeting to lysosome • GO:0022415 viral process • positive regulation of neuron projection development • membrane organization • regulation of endosome organization • regulation of glucosylceramidase activity • regulation of lysosome organization • receptor-mediated endocytosis • aminophospholipid transport • regulation of cellular carbohydrate catabolic process Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	950	n/a
Ensembl	ENSG00000138760	n/a
UniProt	Q14108	n/a
RefSeq (mRNA)	NM_005506 NM_001204255	n/a
RefSeq (protein)	NP_001191184 NP_005497	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn SCARB2 yw SCARB2 a elwir hefyd yn Scavenger receptor class B member 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 4, band 4q21.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn SCARB2.

• AMRF
• EPM4
• LGP85
• CD36L2
• HLGP85
• LIMP-2
• LIMPII
• SR-BII

Llyfryddiaeth

• "The binding of a monoclonal antibody to the apical region of SCARB2 blocks EV71 infection. ". Protein Cell. 2017. PMID 28447294.
• "SCARB2/LIMP2 deficiency in action myoclonus-renal failure syndrome. ". Epileptic Disord. 2016. PMID 27582254.
• "Changes in the expression of LIMP-2 during cerulein-induced pancreatitis in rats: Effect of inhibition of leukocyte infiltration, cAMP and MAPKs early on in its development. ". Int J Biochem Cell Biol. 2016. PMID 26794464.
• Action Myoclonus - Renal Failure Syndrome. 1993. PMID 26677510.
• "Increased expression of lysosome membrane protein 2 in glomeruli of patients with idiopathic membranous nephropathy.". Proteomics. 2015. PMID 26304790.