S100A7

S100A7
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1PSR, 2PSR, 2WND, 2WOR, 2WOS, 3PSR, 4AQJ
Dynodwyr
Cyfenwau	S100A7, PSOR1, S100A7c, S100 calcium binding protein A7
Dynodwyr allanol	OMIM: 600353 HomoloGene: 48150 GeneCards: S100A7
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • calcium ion binding • zinc ion binding • metal ion binding • GO:0001948, GO:0016582 protein binding • RAGE receptor binding • transition metal ion binding Cydrannau o'r gell • cytoplasm • cytosol • focal adhesion • extracellular region • Reticwlwm endoplasmig • cnewyllyn cell • azurophil granule lumen • extracellular space • GO:0005578 extracellular matrix • collagen-containing extracellular matrix Prosesau biolegol • GO:0001315 response to reactive oxygen species • positive regulation of monocyte chemotaxis • keratinocyte differentiation • positive regulation of granulocyte chemotaxis • sequestering of metal ion • response to lipopolysaccharide • positive regulation of T cell chemotaxis • angiogenesis • positive regulation of ERK1 and ERK2 cascade • epidermis development • innate immune response • antimicrobial humoral response • neutrophil degranulation • antimicrobial humoral immune response mediated by antimicrobial peptide Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	6278	n/a
Ensembl	ENSG00000143556	n/a
UniProt	P31151	n/a
RefSeq (mRNA)	NM_002963	n/a
RefSeq (protein)	NP_002954	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn S100A7 yw S100A7 a elwir hefyd yn S100 calcium binding protein A7 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 1, band 1q21.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn S100A7.

• PSOR1
• S100A7c

Llyfryddiaeth

• "Overexpression of Psoriasin (S100A7) Contributes to Dysregulated Differentiation in Psoriasis. ". Acta Derm Venereol. 2017. PMID 27958610.
• "Salivary psoriasin (S100A7) correlates with diffusion capacity of carbon monoxide in a large cohort of systemic sclerosis patients. ". J Transl Med. 2016. PMID 27608975.
• "Biochemical and Functional Evaluation of the Intramolecular Disulfide Bonds in the Zinc-Chelating Antimicrobial Protein Human S100A7 (Psoriasin). ". Biochemistry. 2017. PMID 28976190.
• "S100A7: from mechanism to cancer therapy. ". Oncogene. 2017. PMID 28825725.
• "Psoriasin promotes invasion, aggregation and survival of pancreatic cancer cells; association with disease progression.". Int J Oncol. 2017. PMID 28393239.