GRAP2

GRAP2
Dynodwyr
Cyfenwau	GRAP2, GADS, GRAP-2, GRB2L, GRBLG, GRID, GRPL, GrbX, Grf40, Mona, P38, GRB2-related adaptor protein 2, GRB2 related adaptor protein 2
Dynodwyr allanol	OMIM: 604518 HomoloGene: 21007 GeneCards: GRAP2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • non-membrane spanning protein tyrosine kinase activity • signaling receptor binding Cydrannau o'r gell • cytoplasm • cytosol • endosome • cnewyllyn cell • extrinsic component of cytoplasmic side of plasma membrane Prosesau biolegol • Fc-epsilon receptor signaling pathway • cell-cell signaling • T cell costimulation • Ras protein signal transduction • T cell receptor signaling pathway • positive regulation of signal transduction • transmembrane receptor protein tyrosine kinase signaling pathway • cell migration • cell differentiation • peptidyl-tyrosine autophosphorylation • regulation of cell population proliferation • innate immune response Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	9402	n/a
Ensembl	ENSG00000100351	n/a
UniProt	O75791	n/a
RefSeq (mRNA)	NM_001291824 NM_001291825 NM_001291826 NM_001291828 NM_004810	n/a
RefSeq (protein)	NP_001278753 NP_001278754 NP_001278755 NP_001278757 NP_004801	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn GRAP2 yw GRAP2 a elwir hefyd yn GRB2-related adaptor protein 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 22, band 22q13.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn GRAP2.

• P38
• GADS
• GRID
• GRPL
• GrbX
• Mona
• GRB2L
• GRBLG
• Grf40
• GRAP-2

Llyfryddiaeth

• "Upstream open reading frames regulate translation of Mona/Gads adapter mRNA in the megakaryocytic lineage. ". Platelets. 2002. PMID 12487779.
• "Genomic organization and restricted expression of the human Mona/Gads gene suggests regulation by two specific promoters. ". Gene. 2002. PMID 12062812.
• "GADS is required for TCR-mediated calcium influx and cytokine release, but not cellular adhesion, in human T cells. ". Cell Signal. 2015. PMID 25636200.
• "Expression of the Grb2-related RET adapter protein Grap-2 in human medullary thyroid carcinoma. ". Cancer Lett. 2009. PMID 19027225.
• "Grap-2, a novel RET binding protein, is involved in RET mitogenic signaling.". Oncogene. 2003. PMID 12917638.