GMEB1

GMEB1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1OQJ
Dynodwyr
Cyfenwau	GMEB1, P96PIF, PIF96, glucocorticoid modulatory element binding protein 1
Dynodwyr allanol	OMIM: 604409 HomoloGene: 10647 GeneCards: GMEB1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity • DNA binding • GO:0001105 transcription coactivator activity • GO:0001077, GO:0001212, GO:0001213, GO:0001211, GO:0001205 DNA-binding transcription activator activity, RNA polymerase II-specific • metal ion binding • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific Cydrannau o'r gell • cytoplasm • cnewyllyn cell • nucleoplasm Prosesau biolegol • GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II • GO:0009373 regulation of transcription, DNA-templated • transcription by RNA polymerase II • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II • transcription, DNA-templated Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	10691	n/a
Ensembl	ENSG00000162419	n/a
UniProt	Q9Y692	n/a
RefSeq (mRNA)	NM_006582 NM_024482 NM_001319674	n/a
RefSeq (protein)	NP_001306603 NP_006573 NP_077808	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn GMEB1 yw GMEB1 a elwir hefyd yn Glucocorticoid modulatory element binding protein 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 1, band 1p35.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn GMEB1.

• PIF96
• P96PIF

Llyfryddiaeth

• "Regulation of procaspase-2 by glucocorticoid modulatory element-binding protein 1 through the interaction with caspase recruitment domain. ". Biochem Biophys Res Commun. 2004. PMID 15555560.
• "A consensus DNA recognition motif for two KDWK transcription factors identifies flexible-length, CpG-methylation sensitive cognate binding sites in the majority of human promoters. ". J Mol Biol. 2001. PMID 11743720.
• "GMEB1, a novel endogenous caspase inhibitor, prevents hypoxia- and oxidative stress-induced neuronal apoptosis. ". Neurosci Lett. 2008. PMID 18455874.
• "Crystal structure and nuclear magnetic resonance analyses of the SAND domain from glucocorticoid modulatory element binding protein-1 reveals deoxyribonucleic acid and zinc binding regions. ". Mol Endocrinol. 2003. PMID 12702733.
• "Cloning and characterization of hGMEB1, a novel glucocorticoid modulatory element binding protein.". FEBS Lett. 1999. PMID 10386584.