GABPB1

GABPB1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1AWC
Dynodwyr
Cyfenwau	GABPB1, BABPB2, E4TF1, E4TF1-47, E4TF1-53, E4TF1B, GABPB, GABPB2, NRF2B1, NRF2B2, GABPB-1, GA binding protein transcription factor beta subunit 1, GA binding protein transcription factor subunit beta 1
Dynodwyr allanol	OMIM: 600610 HomoloGene: 7723 GeneCards: GABPB1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity • protein heterodimerization activity • GO:0001948, GO:0016582 protein binding Cydrannau o'r gell • cnewyllyn cell • nucleoplasm • cytoplasmic ribonucleoprotein granule Prosesau biolegol • GO:0009373 regulation of transcription, DNA-templated • mitochondrion organization • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II • GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II • transcription, DNA-templated Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	2553	n/a
Ensembl	ENSG00000104064	n/a
UniProt	Q06547	n/a
RefSeq (mRNA)	NM_002041 NM_005254 NM_016654 NM_016655 NM_181427 NM_001320910 NM_001320915	n/a
RefSeq (protein)	NP_001307839 NP_001307844 NP_002032 NP_005245 NP_057738 NP_057739 NP_852092 NP_057738.1	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn GABPB1 yw GABPB1 a elwir hefyd yn GA binding protein transcription factor beta subunit 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 15, band 15q21.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn GABPB1.

• E4TF1
• GABPB
• BABPB2
• E4TF1B
• GABPB2
• NRF2B1
• NRF2B2
• GABPB-1
• E4TF1-47
• E4TF1-53

Llyfryddiaeth

• "GABP is necessary for stem/progenitor cell maintenance and myeloid differentiation in human hematopoiesis and chronic myeloid leukemia. ". Stem Cell Res. 2016. PMID 27100840.
• "Retinoblastoma binding factor 1 site in the core promoter region of the human RB gene is activated by hGABP/E4TF1. ". Cancer Res. 1997. PMID 9242441.
• "Nuclear respiratory factors 1 and 2 utilize similar glutamine-containing clusters of hydrophobic residues to activate transcription. ". Mol Cell Biol. 1996. PMID 8816484.
• "Identity of GABP with NRF-2, a multisubunit activator of cytochrome oxidase expression, reveals a cellular role for an ETS domain activator of viral promoters. ". Genes Dev. 1993. PMID 8383622.
• "Nuclear Respiratory Factor 2β (NRF-2β) recruits NRF-2α to the nucleus by binding to importin-α:β via an unusual monopartite-type nuclear localization signal.". J Mol Biol. 2013. PMID 23856623.