FSCN1

FSCN1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1DFC, 4GP0, 4GP3, 3P53, 4GOY, 4GOV, 3LLP
Dynodwyr
Cyfenwau	FSCN1, FAN1, HSN, SNL, p55, fascin actin-bundling protein 1
Dynodwyr allanol	OMIM: 602689 HomoloGene: 48164 GeneCards: FSCN1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • protein-macromolecule adaptor activity • actin filament binding • GO:0001948, GO:0016582 protein binding • actin binding • RNA binding • cadherin binding Cydrannau o'r gell • cytoplasm • cell projection • cell-cell junction • filopodium • ruffle • myelin sheath • stress fiber • microvillus • cell junction • microspike • cell projection membrane • actin cytoskeleton • podosome • extracellular exosome • Cytosgerbwd • growth cone • lamellipodium • filamentous actin • cytosol Prosesau biolegol • regulation of microvillus assembly • establishment of apical/basal cell polarity • regulation of actin cytoskeleton organization • actin filament organization • cell motility • positive regulation of podosome assembly • actin filament bundle assembly • positive regulation of extracellular matrix disassembly • cell-cell junction assembly • microspike assembly • cell population proliferation • positive regulation of lamellipodium assembly • cell migration • positive regulation of filopodium assembly • actin cytoskeleton organization • anatomical structure morphogenesis • establishment or maintenance of cell polarity • cytokine-mediated signaling pathway Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	6624	n/a
Ensembl	ENSG00000075618	n/a
UniProt	Q16658	n/a
RefSeq (mRNA)	NM_003088	n/a
RefSeq (protein)	NP_003079	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn FSCN1 yw FSCN1 a elwir hefyd yn Fascin actin-bundling protein 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 7, band 7p22.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn FSCN1.

• HSN
• SNL
• p55
• FAN1

Llyfryddiaeth

• "TGF-β1 promotes the migration and invasion of bladder carcinoma cells by increasing fascin1 expression. ". Oncol Rep. 2016. PMID 27350089.
• "Fascin-1 as a novel diagnostic marker of triple-negative breast cancer. ". Cancer Med. 2016. PMID 27184764.
• "Fascin phosphorylation sites combine to regulate esophageal squamous cancer cell behavior. ". Amino Acids. 2017. PMID 28251354.
• "The Tax-Inducible Actin-Bundling Protein Fascin Is Crucial for Release and Cell-to-Cell Transmission of Human T-Cell Leukemia Virus Type 1 (HTLV-1). ". PLoS Pathog. 2016. PMID 27776189.
• "The clinical significance of fascin expression in a newly diagnosed primary glioblastoma.". J Neurooncol. 2016. PMID 27406586.