EED

EED
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 3IIW, 3IIY, 3IJ0, 3IJ1, 3IJC, 3JPX, 3JZG, 3JZH, 3JZN, 3K26, 3K27, 4X3E, 5IJ7, 5IJ8, 5HYN
Dynodwyr
Cyfenwau	EED, HWAIT1, embryonic ectoderm development, COGIS
Dynodwyr allanol	OMIM: 605984 HomoloGene: 2814 GeneCards: EED
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • chromatin binding • GO:0001948, GO:0016582 protein binding • identical protein binding • GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding • histone methyltransferase activity • histone methyltransferase activity (H3-K27 specific) • nucleosome binding Cydrannau o'r gell • sex chromatin • ESC/E(Z) complex • Cromosom • pronucleus • cnewyllyn cell • nucleoplasm • cytosol Prosesau biolegol • regulation of gene expression by genetic imprinting • GO:0009373 regulation of transcription, DNA-templated • GO:1901227 negative regulation of transcription by RNA polymerase II • transcription, DNA-templated • negative regulation of gene expression, epigenetic • spinal cord development • positive regulation of histone H3-K27 methylation • histone methylation • GO:0045996 negative regulation of transcription, DNA-templated • regulation of adaxial/abaxial pattern formation • histone H3-K27 methylation • cellular response to leukemia inhibitory factor • negative regulation of G0 to G1 transition • GO:0031497, GO:0006336, GO:0034724, GO:0001301, GO:0007580, GO:0034652, GO:0010847 chromatin organization Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	8726	n/a
Ensembl	ENSG00000074266	n/a
UniProt	O75530	n/a
RefSeq (mRNA)	NM_001308007 NM_003797 NM_152991 NM_001330334	n/a
RefSeq (protein)	NP_001294936 NP_001317263 NP_003788	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn EED yw EED a elwir hefyd yn Embryonic ectoderm development (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 11, band 11q14.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn EED.

• HEED
• COGIS
• WAIT1

Llyfryddiaeth

• "EED gene polymorphism in patients with colorectal cancer. ". Int J Biol Markers. 2013. PMID 23709348.
• "EED mutants impair polycomb repressive complex 2 in myelodysplastic syndrome and related neoplasms. ". Leukemia. 2012. PMID 22733077.
• "Novel EED mutation in patient with Weaver syndrome. ". Am J Med Genet A. 2017. PMID 27868325.
• "EED-associated overgrowth in a second male patient. ". J Hum Genet. 2016. PMID 27193220.
• "EED regulates epithelial-mesenchymal transition of cancer cells induced by TGF-β.". Biochem Biophys Res Commun. 2014. PMID 25264103.