ECI2

ECI2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2CQU, 2F6Q, 4U18, 4U19, 4U1A
Dynodwyr
Cyfenwau	ECI2, ACBD2, DRS-1, DRS1, HCA88, PECI, dJ1013A10.3, enoyl-CoA delta isomerase 2
Dynodwyr allanol	OMIM: 608024 HomoloGene: 38145 GeneCards: ECI2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • intramolecular oxidoreductase activity, transposing C=C bonds • signaling receptor binding • catalytic activity • isomerase activity • fatty-acyl-CoA binding • dodecenoyl-CoA delta-isomerase activity Cydrannau o'r gell • bilen • mitocondria • intracellular membrane-bounded organelle • nucleoplasm • peroxisomal matrix • peroxisome • cytosol Prosesau biolegol • fatty acid catabolic process • fatty acid beta-oxidation • metabolaeth • fatty acid beta-oxidation using acyl-CoA oxidase • protein targeting to peroxisome Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	10455	n/a
Ensembl	ENSG00000198721	n/a
UniProt	O75521	n/a
RefSeq (mRNA)	NM_001166010 NM_006117 NM_206836	n/a
RefSeq (protein)	NP_001159482 NP_006108 NP_996667	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn ECI2 yw ECI2 a elwir hefyd yn Enoyl-CoA delta isomerase 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 6, band 6p25.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn ECI2.

• DRS1
• PECI
• ACBD2
• DRS-1
• HCA88
• dJ1013A10.3

Llyfryddiaeth

• "Human Δ³,Δ²-enoyl-CoA isomerase, type 2: a structural enzymology study on the catalytic role of its ACBP domain and helix-10. ". FEBS J. 2015. PMID 25515061.
• "Disruption of mitochondrial beta -oxidation of unsaturated fatty acids in the 3,2-trans-enoyl-CoA isomerase-deficient mouse. ". J Biol Chem. 2002. PMID 11916962.
• "ACBD2/ECI2-Mediated Peroxisome-Mitochondria Interactions in Leydig Cell Steroid Biosynthesis. ". Mol Endocrinol. 2016. PMID 27167610.
• "Diazepam-binding inhibitor-related protein 1: a candidate autoantigen in acquired aplastic anemia patients harboring a minor population of paroxysmal nocturnal hemoglobinuria-type cells. ". Blood. 2004. PMID 15217832.
• "Molecular cloning and expression of a novel human cDNA related to the diazepam binding inhibitor.". Biochim Biophys Acta. 1999. PMID 10354522.