CHN2

CHN2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1XA6
Dynodwyr
Cyfenwau	CHN2, ARHGAP3, BCH, CHN2-3, RHOGAP3, chimerin 2
Dynodwyr allanol	OMIM: 602857 HomoloGene: 31213 GeneCards: CHN2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • metal ion binding • GO:0005097, GO:0005099, GO:0005100 GTPase activator activity Cydrannau o'r gell • cytoplasm • cytosol • bilen Prosesau biolegol • GO:0007243 intracellular signal transduction • regulation of small GTPase mediated signal transduction • GO:0072468 signal transduction • positive regulation of signal transduction • GO:0032320, GO:0032321, GO:0032855, GO:0043089, GO:0032854 positive regulation of GTPase activity • GO:0043087, GO:0032313, GO:0032319, GO:0032314, GO:0043088 regulation of GTPase activity Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	1124	n/a
Ensembl	ENSG00000106069	n/a
UniProt	P52757	n/a
RefSeq (mRNA)	NM_001039936 NM_001293069 NM_001293070 NM_001293071 NM_001293072 NM_001293073 NM_001293075 NM_001293076 NM_001293077 NM_001293078 NM_001293079 NM_001293080 NM_001293081 NM_004067 NM_001398427	n/a
RefSeq (protein)	NP_001035025 NP_001279998 NP_001279999 NP_001280000 NP_001280001 NP_001280002 NP_001280004 NP_001280005 NP_001280006 NP_001280007 NP_001280008 NP_001280009 NP_001280010 NP_004058	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CHN2 yw CHN2 a elwir hefyd yn Beta chimaerin isoform B2-CHNdel ex7p-13p (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 7, band 7p14.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CHN2.

• BCH
• CHN2-3
• ARHGAP3
• RHOGAP3

Llyfryddiaeth

• "Chimerin 2 genetic polymorphisms are associated with non-proliferative diabetic retinopathy in Taiwanese type 2 diabetic patients. ". J Diabetes Complications. 2014. PMID 24854763.
• "Association of a novel polymorphism of the β2-chimaerin gene (CHN2) with smoking. ". J Investig Med. 2013. PMID 23941981.
• "Tyrosine phosphorylation of beta2-chimaerin by Src-family kinase negatively regulates its Rac-specific GAP activity. ". Biochim Biophys Acta. 2007. PMID 17560670.
• "Regulation of vascular smooth muscle proliferation and migration by beta2-chimaerin, a non-protein kinase C phorbol ester receptor. ". Int J Mol Med. 2006. PMID 16525710.
• "Beta2-chimaerin provides a diacylglycerol-dependent mechanism for regulation of adhesion and chemotaxis of T cells.". J Cell Sci. 2006. PMID 16352660.