CANX

CANX
Dynodwyr
Cyfenwau	CANX, CNX, IP90, P90, calnexin
Dynodwyr allanol	OMIM: 114217 HomoloGene: 1324 GeneCards: CANX
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • calcium ion binding • apolipoprotein binding • unfolded protein binding • metal ion binding • ionotropic glutamate receptor binding • carbohydrate binding • RNA binding • GO:0001948, GO:0016582 protein binding Cydrannau o'r gell • cytoplasm • integral component of membrane • mitochondria-associated endoplasmic reticulum membrane • rough endoplasmic reticulum • ribosom • endoplasmic reticulum lumen • endoplasmic reticulum membrane • bilen • melanosome • myelin sheath • dendritic spine • smooth endoplasmic reticulum • axon • neuronal cell body • Reticwlwm endoplasmig • dendrite cytoplasm • integral component of lumenal side of endoplasmic reticulum membrane • extracellular exosome • GO:0005578 extracellular matrix • GO:0009327 protein-containing complex • endoplasmic reticulum quality control compartment • glutamatergic synapse • integral component of postsynaptic membrane • integral component of presynaptic active zone membrane Prosesau biolegol • antigen processing and presentation of exogenous peptide antigen via MHC class II • antigen processing and presentation of peptide antigen via MHC class I • GO:0010260 heneiddio • protein folding in endoplasmic reticulum • protein secretion • clathrin-dependent endocytosis • synaptic vesicle endocytosis • protein folding • chaperone-mediated protein folding • interleukin-12-mediated signaling pathway • interleukin-27-mediated signaling pathway • interleukin-35-mediated signaling pathway Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	821	n/a
Ensembl	ENSG00000283777 ENSG00000127022	n/a
UniProt	P27824	n/a
RefSeq (mRNA)	NM_001024649 NM_001746	n/a
RefSeq (protein)	NP_001019820 NP_001737 NP_001350922 NP_001350923 NP_001350924 NP_001350925 NP_001350926 NP_001350927 NP_001350928 NP_001350929 NP_001350930	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CANX yw CANX a elwir hefyd yn Calnexin (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 5, band 5q35.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CANX.

• CNX
• P90
• IP90

Llyfryddiaeth

• "Calnexin, an ER-induced protein, is a prognostic marker and potential therapeutic target in colorectal cancer. ". J Transl Med. 2016. PMID 27369741.
• "Model-Driven Understanding of Palmitoylation Dynamics: Regulated Acylation of the Endoplasmic Reticulum Chaperone Calnexin. ". PLoS Comput Biol. 2016. PMID 26900856.
• "Purification and characterization of a soluble calnexin from human placenta. ". Protein Expr Purif. 2013. PMID 24056258.
• "Role of cysteine amino acid residues in calnexin. ". Mol Cell Biochem. 2012. PMID 21842374.
• "Polypeptide substrate recognition by calnexin requires specific conformations of the calnexin protein.". J Biol Chem. 2005. PMID 16061483.