ARPC2

ARPC2
Dynodwyr
Cyfenwau	ARPC2, ARC34, PNAS-139, p34-Arc, PRO2446, actin related protein 2/3 complex subunit 2
Dynodwyr allanol	OMIM: 604224 HomoloGene: 4187 GeneCards: ARPC2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • actin filament binding • structural constituent of cytoskeleton • GO:0001948, GO:0016582 protein binding • actin binding Cydrannau o'r gell • cytosol • endosome • cell projection • muscle cell projection membrane • focal adhesion • Cellbilen • arp2/3 protein complex • synapse • cell junction • cell leading edge • actin cytoskeleton • neuron projection • extracellular exosome • Cytosgerbwd • cytoplasm • cnewyllyn cell • lamellipodium • site of double-strand break • glutamatergic synapse Prosesau biolegol • positive regulation of actin filament polymerization • Fc-gamma receptor signaling pathway involved in phagocytosis • ephrin receptor signaling pathway • regulation of actin filament polymerization • positive regulation of substrate adhesion-dependent cell spreading • Arp2/3 complex-mediated actin nucleation • positive regulation of lamellipodium assembly • membrane organization • actin filament polymerization • actin polymerization-dependent cell motility Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	10109	n/a
Ensembl	ENSG00000163466	n/a
UniProt	O15144	n/a
RefSeq (mRNA)	NM_005731 NM_152862	n/a
RefSeq (protein)	NP_005722 NP_690601	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn ARPC2 yw ARPC2 a elwir hefyd yn Actin related protein 2/3 complex subunit 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 2, band 2q35.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn ARPC2.

• ARC34
• PRO2446
• p34-Arc
• PNAS-139

Llyfryddiaeth

• "Filopodia initiation: focus on the Arp2/3 complex and formins. ". Cell Adh Migr. 2011. PMID 21975549.
• "Overexpression of N-WASP in the brain of human epilepsy. ". Brain Res. 2008. PMID 18708039.
• "Altered Expression of ARP2/3 Complex Signaling Pathway Genes in Prefrontal Layer 3 Pyramidal Cells in Schizophrenia. ". Am J Psychiatry. 2017. PMID 27523502.
• "Forkhead Box F1 represses cell growth and inhibits COL1 and ARPC2 expression in lung fibroblasts in vitro. ". Am J Physiol Lung Cell Mol Physiol. 2014. PMID 25260753.
• "Dynamics between actin and the VE-cadherin/catenin complex: novel aspects of the ARP2/3 complex in regulation of endothelial junctions.". Cell Adh Migr. 2014. PMID 24621569.