ADAMTS1

ADAMTS1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2JIH, 2V4B, 3Q2G, 3Q2H
Dynodwyr
Cyfenwau	ADAMTS1, C3-C5, METH1, ADAM metallopeptidase with thrombospondin type 1 motif 1
Dynodwyr allanol	OMIM: 605174 HomoloGene: 21381 GeneCards: ADAMTS1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • heparin binding • zinc ion binding • metal ion binding • GO:0070122 peptidase activity • metalloendopeptidase activity • hydrolase activity • metallopeptidase activity Cydrannau o'r gell • extracellular region • basement membrane • GO:0016023 cytoplasmic vesicle • GO:0005578 extracellular matrix • collagen-containing extracellular matrix Prosesau biolegol • ovulation from ovarian follicle • heart trabecula formation • kidney development • proteolysis • integrin-mediated signaling pathway • negative regulation of cell population proliferation • positive regulation of G1/S transition of mitotic cell cycle • positive regulation of vascular associated smooth muscle cell proliferation • positive regulation of vascular associated smooth muscle cell migration Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	9510	n/a
Ensembl	ENSG00000154734	n/a
UniProt	Q9UHI8	n/a
RefSeq (mRNA)	NM_006988	n/a
RefSeq (protein)	NP_008919	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn ADAMTS1 yw ADAMTS1 a elwir hefyd yn ADAM metallopeptidase with thrombospondin type 1 motif 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 21, band 21q21.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn ADAMTS1.

• C3-C5
• METH1

Llyfryddiaeth

• "[Association of ADAMTS-1 gene polymorphisms with ischemic stroke caused by large artery atherosclerosis]. ". Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2015. PMID 26663063.
• "The ADAMTS1 Gene Is Associated with Familial Mandibular Prognathism. ". J Dent Res. 2015. PMID 26124221.
• "Diverse Functions of a Disintegrin and Metalloproteinase with Thrombospondin Motif-1. ". Yakugaku Zasshi. 2017. PMID 28674292.
• "ADAMTS-1 Is Found in the Nuclei of Normal and Tumoral Breast Cells. ". PLoS One. 2016. PMID 27764205.
• "Evaluation of the relationship and genetic overlap between Kashin-Beck disease and body mass index.". Scand J Rheumatol. 2016. PMID 27053287.