ZNF224

ZNF224
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2ELY, 2ELZ, 2EM0, 2EM6, 2EM7, 2EM8, 2EM9, 2EN1, 2EN8, 2ENA, 2ENC, 2EOQ, 2EOR, 2EQ4, 2YSP, 2YTH
Dynodwyr
Cyfenwau	ZNF224, BMZF-2, BMZF2, KOX22, ZNF255, ZNF27, ZNF233, zinc finger protein 224
Dynodwyr allanol	OMIM: 194555 HomoloGene: 130663 GeneCards: ZNF224
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • nucleic acid binding • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity • metal ion binding • DNA binding • GO:0001078, GO:0001214, GO:0001206 DNA-binding transcription repressor activity, RNA polymerase II-specific • sequence-specific DNA binding • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific Cydrannau o'r gell • cnewyllyn cell • intracellular anatomical structure • nuclear membrane • transcription repressor complex Prosesau biolegol • GO:0045996 negative regulation of transcription, DNA-templated • GO:0009373 regulation of transcription, DNA-templated • transcription, DNA-templated • GO:1901227 negative regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	7767	n/a
Ensembl	ENSG00000267680	n/a
UniProt	Q9NZL3	n/a
RefSeq (mRNA)	NM_013398 NM_001321645	n/a
RefSeq (protein)	NP_001308574 NP_037530	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn ZNF224 yw ZNF224 a elwir hefyd yn Zinc finger protein 224 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 19, band 19q13.31.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn ZNF224.

• BMZF2
• KOX22
• ZNF27
• BMZF-2
• ZNF233
• ZNF255

Llyfryddiaeth

• "Differential expression and cellular localization of ZNF224 and ZNF255, two isoforms of the Krüppel-like zinc-finger protein family. ". Gene. 2007. PMID 17900823.
• "A novel zinc finger transcriptional repressor, ZNF224, interacts with the negative regulatory element (AldA-NRE) and inhibits gene expression. ". FEBS Lett. 2003. PMID 12527367.
• "The Complex Role of the ZNF224 Transcription Factor in Cancer. ". Adv Protein Chem Struct Biol. 2017. PMID 28215224.
• "ZNF224, Krüppel like zinc finger protein, induces cell growth and apoptosis-resistance by down-regulation of p21 and p53 via miR-663a. ". Oncotarget. 2016. PMID 27105517.
• "ZNF224: Structure and role of a multifunctional KRAB-ZFP protein.". Int J Biochem Cell Biol. 2011. PMID 21187159.