ZHX1

ZHX1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2ECB, 2GHF, 2LY9, 3NAR
Dynodwyr
Cyfenwau	ZHX1, zinc fingers and homeoboxes 1
Dynodwyr allanol	OMIM: 604764 HomoloGene: 5225 GeneCards: ZHX1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity • DNA binding • GO:0001948, GO:0016582 protein binding • GO:0001106 transcription corepressor activity • metal ion binding • protein heterodimerization activity • nucleic acid binding • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific Cydrannau o'r gell • cnewyllyn cell • nucleoplasm Prosesau biolegol • cell differentiation • GO:0045996 negative regulation of transcription, DNA-templated • GO:0009373 regulation of transcription, DNA-templated • GO:1901227 negative regulation of transcription by RNA polymerase II • transcription, DNA-templated Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	11244	n/a
Ensembl	ENSG00000165156	n/a
UniProt	Q9UKY1	n/a
RefSeq (mRNA)	NM_001017926 NM_007222	n/a
RefSeq (protein)	NP_001017926 NP_009153	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn ZHX1 yw ZHX1 a elwir hefyd yn Zinc fingers and homeoboxes 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 8, band 8q24.13.

Llyfryddiaeth

• "The tandem zinc-finger region of human ZHX adopts a novel C2H2 zinc finger structure with a C-terminal extension. ". Biochemistry. 2009. PMID 19348505.
• "ZHX1 Promotes the Proliferation, Migration and Invasion of Cholangiocarcinoma Cells. ". PLoS One. 2016. PMID 27835650.
• "Roles of zinc-fingers and homeoboxes 1 during the proliferation, migration, and invasion of glioblastoma cells. ". Tumour Biol. 2017. PMID 28351300.
• "Construction of a recombinant eukaryotic human ZHX1 gene expression plasmid and the role of ZHX1 in hepatocellular carcinoma. ". Mol Med Rep. 2013. PMID 24064680.
• "Novel structural features in two ZHX homeodomains derived from a systematic study of single and multiple domains.". BMC Struct Biol. 2010. PMID 20509910.