ZFP36L1

ZFP36L1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1W0V, 1W0W
Dynodwyr
Cyfenwau	ZFP36L1, BRF1, Berg36, ERF-1, ERF1, RNF162B, TIS11B, cMG1, ZFP36 ring finger protein-like 1, ZFP36 ring finger protein like 1
Dynodwyr allanol	OMIM: 601064 HomoloGene: 31276 GeneCards: ZFP36L1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • DNA binding • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity • metal ion binding • GO:0001948, GO:0016582 protein binding • mRNA binding • 14-3-3 protein binding • RNA binding • mRNA 3'-UTR AU-rich region binding • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific • mRNA 3'-UTR binding Cydrannau o'r gell • cytoplasm • cnewyllyn cell • cytosol • P-body • ribonucleoprotein complex Prosesau biolegol • spongiotrophoblast layer development • mRNA catabolic process • multicellular organism growth • embryonic organ development • chorio-allantoic fusion • vasculogenesis • proepicardium development • heart development • nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay • neural tube development • cell population proliferation • regulation of translation • GO:0097285 apoptotic process • T cell differentiation in thymus • regulation of gene expression • negative regulation of erythrocyte differentiation • cellular response to insulin stimulus • cellular response to phorbol 13-acetate 12-myristate • ERK1 and ERK2 cascade • positive regulation of intracellular mRNA localization • cellular response to glucocorticoid stimulus • cellular response to transforming growth factor beta stimulus • regulation of keratinocyte differentiation • response to wounding • positive regulation of monocyte differentiation • GO:0009373 regulation of transcription, DNA-templated • cellular response to hypoxia • regulation of keratinocyte apoptotic process • regulation of keratinocyte proliferation • phosphatidylinositol 3-kinase signaling • cellular response to tumor necrosis factor • cellular response to epidermal growth factor stimulus • regulation of mRNA 3'-end processing • MAPK cascade • mRNA processing • multicellular organism development • nuclear-transcribed mRNA catabolic process, deadenylation-independent decay • p38MAPK cascade • regulation of mRNA stability • protein kinase B signaling • cellular response to fibroblast growth factor stimulus • regulation of B cell differentiation • positive regulation of fat cell differentiation • regulation of myoblast differentiation • mesendoderm development • mRNA transport • 3'-UTR-mediated mRNA destabilization • cellular response to cAMP • cellular response to peptide hormone stimulus • cellular response to salt stress • regulation of stem cell proliferation • cellular response to raffinose • positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay • negative regulation of mitotic cell cycle phase transition • GO:0015915 transport • GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	677	n/a
Ensembl	ENSG00000185650	n/a
UniProt	Q07352	n/a
RefSeq (mRNA)	NM_004926 NM_001244698 NM_001244701	n/a
RefSeq (protein)	NP_001231627 NP_001231630 NP_004917	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn ZFP36L1 yw ZFP36L1 a elwir hefyd yn ZFP36 ring finger protein like 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 14, band 14q24.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn ZFP36L1.

• BRF1
• ERF1
• cMG1
• ERF-1
• Berg36
• TIS11B
• RNF162B

Llyfryddiaeth

• "Involvement of Tis11b, an AU-rich binding protein, in induction of apoptosis by rituximab in B cell chronic lymphocytic leukemia cells. ". Leukemia. 2009. PMID 19092855.
• "Distinct mechanisms for rescue from apoptosis in Ramos human B cells by signaling through CD40 and interleukin-4 receptor: role for inhibition of an early response gene, Berg36. ". Eur J Immunol. 1996. PMID 8898945.
• "Coding sequence of ERF-1, the human homologue of Tis11b/cMG1, members of the Tis11 family of early response genes. ". Nucleic Acids Res. 1993. PMID 8346037.
• "Cloning and characterization of ERF-1, a human member of the Tis11 family of early-response genes. ". DNA Cell Biol. 1994. PMID 8024689.
• "Transcription factor HNF1beta and novel partners affect nephrogenesis.". Kidney Int. 2008. PMID 18418350.