YWHAB

YWHAB
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2BQ0, 2C23, 4DNK
Dynodwyr
Cyfenwau	YWHAB, GW128, HEL-S-1, HS1, KCIP-1, YWHAA, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
Dynodwyr allanol	OMIM: 601289 HomoloGene: 20724 GeneCards: YWHAB
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001106 transcription corepressor activity • protein domain specific binding • GO:0032403 protein-containing complex binding • histone deacetylase binding • phosphoprotein binding • protein C-terminus binding • GO:0001948, GO:0016582 protein binding • enzyme binding • phosphoserine residue binding • cadherin binding • identical protein binding Cydrannau o'r gell • cytoplasm • bilen • focal adhesion • melanosome • transcription repressor complex • perinuclear region of cytoplasm • extracellular exosome • cytoplasmic vesicle membrane • cnewyllyn cell • mitocondria • cytosol • GO:0009327 protein-containing complex • vacuole • vacuolar membrane Prosesau biolegol • protein targeting • negative regulation of protein dephosphorylation • protein heterooligomerization • regulation of mRNA stability • GO:0048554 positive regulation of catalytic activity • hippo signaling • cytoplasmic sequestering of protein • MAPK cascade • positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway • membrane organization • GO:0022415 viral process • GO:0045996 negative regulation of transcription, DNA-templated • negative regulation of G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	7529	n/a
Ensembl	ENSG00000166913	n/a
UniProt	P31946 Q4VY19	n/a
RefSeq (mRNA)	NM_139323 NM_003404	n/a
RefSeq (protein)	NP_003395 NP_647539	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn YWHAB yw YWHAB a elwir hefyd yn 14-3-3 protein beta/alpha (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 20, band 20q13.12.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn YWHAB.

• HS1
• GW128
• YWHAA
• KCIP-1
• HEL-S-1

Llyfryddiaeth

• "The proteomics of colorectal cancer: identification of a protein signature associated with prognosis. ". PLoS One. 2011. PMID 22125622.
• "Identification of 14-3-3β in human gastric cancer cells and its potency as a diagnostic and prognostic biomarker. ". Proteomics. 2011. PMID 21598387.
• "14-3-3β protein expression in eosinophilic meningitis caused by Angiostrongylus cantonensis infection. ". BMC Res Notes. 2014. PMID 24555778.
• "Modelling cellular signal communication mediated by phosphorylation dependent interaction with 14-3-3 proteins. ". FEBS Lett. 2014. PMID 24269229.
• "Lack of association between 14-3-3 beta gene (YWHAB) polymorphisms and sporadic Creutzfeldt-Jakob disease (CJD).". Mol Biol Rep. 2012. PMID 23053962.