YAF2

YAF2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2D9G
Dynodwyr
Cyfenwau	YAF2, YY1 associated factor 2
Dynodwyr allanol	OMIM: 607534 HomoloGene: 136401 GeneCards: YAF2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • metal ion binding • GO:0001105 transcription coactivator activity • GO:0001106 transcription corepressor activity Cydrannau o'r gell • cnewyllyn cell • cytosol • nucleoplasm Prosesau biolegol • GO:0060469, GO:0009371 positive regulation of transcription, DNA-templated • GO:0045996 negative regulation of transcription, DNA-templated • GO:0009373 regulation of transcription, DNA-templated • transcription, DNA-templated • negative regulation of G0 to G1 transition Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	10138	n/a
Ensembl	ENSG00000015153	n/a
UniProt	Q8IY57	n/a
RefSeq (mRNA)	NM_001012424 NM_001190977 NM_001190979 NM_001190980 NM_005748 NM_001320080	n/a
RefSeq (protein)	NP_001177906 NP_001177908 NP_001177909 NP_001307009 NP_005739	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn YAF2 yw YAF2 a elwir hefyd yn YY1 associated factor 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 12, band 12q12.

Llyfryddiaeth

• "Yaf2 inhibits Myc biological function.". Cancer Lett. 2003. PMID 12706874.
• "Functional interaction of Yaf2 with the central region of MycN.". Oncogene. 2001. PMID 11593398.
• "Yeast two-hybrid cloning of a novel zinc finger protein that interacts with the multifunctional transcription factor YY1.". Nucleic Acids Res. 1997. PMID 9016636.
• "YAF2 promotes TP53-mediated genotoxic stress response via stabilization of PDCD5.". Biochim Biophys Acta. 2015. PMID 25603536.
• "YY1 DNA binding and interaction with YAF2 is essential for Polycomb recruitment.". Nucleic Acids Res,. 2014. PMID 24285299.