WIPF1

WIPF1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2A41
Dynodwyr
Cyfenwau	WIPF1, PRPL-2, WASPIP, WIP, WAS2, WAS/WASL interacting protein family member 1
Dynodwyr allanol	OMIM: 602357 HomoloGene: 86891 GeneCards: WIPF1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • actin binding • profilin binding • GO:0001948, GO:0016582 protein binding • SH3 domain binding • actin filament binding Cydrannau o'r gell • actin cytoskeleton • cytoplasm • cytosol • cell projection • ruffle • Cytosgerbwd • GO:0016023 cytoplasmic vesicle • Microffilament • actin cortical patch Prosesau biolegol • actin polymerization or depolymerization • Fc-gamma receptor signaling pathway involved in phagocytosis • response to other organism • actin filament-based movement • GO:0034622 protein-containing complex assembly • actin cortical patch assembly • endocytosis • positive regulation of actin nucleation • actin cortical patch localization Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	7456	n/a
Ensembl	ENSG00000115935	n/a
UniProt	O43516	n/a
RefSeq (mRNA)	NM_001077269 NM_003387	n/a
RefSeq (protein)	NP_001070737 NP_003378 NP_001362761 NP_001362762 NP_001362763 NP_001362764 NP_001362765 NP_001362766 NP_001362767 NP_001362768	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn WIPF1 yw WIPF1 a elwir hefyd yn WAS/WASL-interacting protein family member 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 2, band 2q31.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn WIPF1.

• WIP
• WAS2
• PRPL-2
• WASPIP

Llyfryddiaeth

• "WIP is essential for lytic granule polarization and NK cell cytotoxicity. ". Proc Natl Acad Sci U S A. 2008. PMID 18258743.
• "WASP-interacting protein (WIP): working in polymerisation and much more. ". Trends Cell Biol. 2007. PMID 17949983.
• "WIP remodeling actin behind the scenes: how WIP reshapes immune and other functions. ". Int J Mol Sci. 2012. PMID 22837718.
• "A novel primary human immunodeficiency due to deficiency in the WASP-interacting protein WIP. ". J Exp Med. 2012. PMID 22231303.
• "An expression module of WIPF1-coexpressed genes identifies patients with favorable prognosis in three tumor types.". J Mol Med (Berl). 2009. PMID 19399471.