WIF1

WIF1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2D3J, 2YGN, 2YGO, 2YGP, 2YGQ
Dynodwyr
Cyfenwau	WIF1, WIF-1, WNT inhibitory factor 1
Dynodwyr allanol	OMIM: 605186 HomoloGene: 31430 GeneCards: WIF1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • Wnt-protein binding • GO:0001948, GO:0016582 protein binding • signaling receptor binding Cydrannau o'r gell • extracellular region • cell surface Prosesau biolegol • multicellular organism development • negative regulation of Wnt signaling pathway • Wnt signaling pathway • GO:0072468 signal transduction • positive regulation of fat cell differentiation • GO:1903374 anatomical structure development Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	11197	n/a
Ensembl	ENSG00000156076	n/a
UniProt	Q9Y5W5	n/a
RefSeq (mRNA)	NM_007191	n/a
RefSeq (protein)	NP_009122	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn WIF1 yw WIF1 a elwir hefyd yn WNT inhibitory factor 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 12, band 12q14.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn WIF1.

• WIF-1

Llyfryddiaeth

• "Inhibition of Wnt Inhibitory Factor 1 Under Hypoxic Condition in Human Umbilical Vein Endothelial Cells Promoted Angiogenesis in Vitro. ". Reprod Sci. 2016. PMID 26994065.
• "Aberrant Wnt-1/beta-catenin signaling and WIF-1 deficiency are important events which promote tumor cell invasion and metastasis in salivary gland adenoid cystic carcinoma. ". Biomed Mater Eng. 2015. PMID 26405993.
• "WNT inhibitory factor 1 promoter hypermethylation is an early event during gallbladder cancer tumorigenesis that predicts poor survival. ". Gene. 2017. PMID 28438695.
• "Native Oligodendrocytes in Astrocytomas Might Inhibit Tumor Proliferation by WIF1 Expression. ". J Neuropathol Exp Neurol. 2017. PMID 28040794.
• "Rescued expression of WIF-1 in gallbladder cancer inhibits tumor growth and induces tumor cell apoptosis with altered expression of proteins.". Mol Med Rep. 2016. PMID 27430608.