WFIKKN1

WFIKKN1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2DDI, 2DDJ
Dynodwyr
Cyfenwau	WFIKKN1, C16orf12, RJD2, WFDC20A, WFIKKN, WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1
Dynodwyr allanol	OMIM: 608021 HomoloGene: 14244 GeneCards: WFIKKN1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • peptidase inhibitor activity • GO:0048551 enzyme inhibitor activity • GO:0001948, GO:0016582 protein binding • metalloendopeptidase inhibitor activity • serine-type endopeptidase inhibitor activity • receptor antagonist activity • transforming growth factor beta binding Cydrannau o'r gell • extracellular region Prosesau biolegol • skeletal system development • negative regulation of DNA binding • roof of mouth development • negative regulation of peptidase activity • negative regulation of protein binding • negative regulation of endopeptidase activity • negative regulation of transforming growth factor beta receptor signaling pathway • extracellular negative regulation of signal transduction • negative regulation of signaling receptor activity Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	117166	n/a
Ensembl	ENSG00000127578	n/a
UniProt	Q96NZ8	n/a
RefSeq (mRNA)	NM_053284	n/a
RefSeq (protein)	NP_444514	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn WFIKKN1 yw WFIKKN1 a elwir hefyd yn WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 16, band 16p13.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn WFIKKN1.

• RJD2
• WFIKKN
• WFDC20A
• C16orf12

Llyfryddiaeth

• "Expression, purification and characterization of the second Kunitz-type protease inhibitor domain of the human WFIKKN protein. ". Eur J Biochem. 2003. PMID 12709070.
• "Distinct expression pattern of two related human proteins containing multiple types of protease-inhibitory modules. ". Biol Chem. 2002. PMID 11928817.
• "A human protein containing multiple types of protease-inhibitory modules. ". Proc Natl Acad Sci U S A. 2001. PMID 11274388.
• "Influence of WFIKKN1 on BMP1-mediated activation of latent myostatin. ". FEBS J. 2016. PMID 27782377.
• "Second Kunitz-type protease inhibitor domain of the human WFIKKN1 protein.". J Biomol NMR. 2006. PMID 16791741.