WASF2

WASF2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2A40
Dynodwyr
Cyfenwau	WASF2, IMD2, SCAR2, WASF4, WAVE2, dJ393P12.2, WAS protein family member 2, WASP family member 2
Dynodwyr allanol	OMIM: 605875 HomoloGene: 86743 GeneCards: WASF2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0032403 protein-containing complex binding • GO:0001948, GO:0016582 protein binding • actin binding • SH3 domain binding • cadherin binding • protein kinase A binding Cydrannau o'r gell • cytoplasm • cytosol • cell projection • SCAR complex • cell-cell junction • ruffle • intracellular anatomical structure • early endosome • actin cytoskeleton • extracellular exosome • Cytosgerbwd • lamellipodium • GO:0009327 protein-containing complex • synapse Prosesau biolegol • megakaryocyte development • endocytosis • Fc-gamma receptor signaling pathway involved in phagocytosis • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • actin filament-based movement • vascular endothelial growth factor receptor signaling pathway • angiogenesis • Rac protein signal transduction • GO:0022415 viral process • positive regulation of lamellipodium assembly • negative regulation of stress fiber assembly • ameboidal-type cell migration • lamellipodium morphogenesis • actin cytoskeleton organization • lamellipodium assembly • postsynaptic actin cytoskeleton organization Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	10163	n/a
Ensembl	ENSG00000158195	n/a
UniProt	Q9Y6W5	n/a
RefSeq (mRNA)	NM_006990 NM_001201404	n/a
RefSeq (protein)	NP_001188333 NP_008921	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn WASF2 yw WASF2 a elwir hefyd yn WAS protein family member 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 1, band 1p36.11.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn WASF2.

• IMD2
• SCAR2
• WASF4
• WAVE2
• dJ393P12.2

Llyfryddiaeth

• "Directional control of WAVE2 membrane targeting by EB1 and phosphatidylinositol 3,4,5-triphosphate. ". Cell Signal. 2010. PMID 19925864.
• "WAVE2 is regulated by multiple phosphorylation events within its VCA domain. ". Cell Motil Cytoskeleton. 2009. PMID 19012317.
• "Down-regulation of WAVE2, WASP family verprolin-homologous protein 2, in gastric cancer indicates lymph node metastasis and cell migration. ". Anticancer Res. 2014. PMID 24778020.
• "Decreased expression of Wiskott-Aldrich syndrome protein family verprolin-homologous protein 2 may be involved in the development of pre-eclampsia. ". Reprod Biomed Online. 2014. PMID 24125947.
• "ERK-MAPK drives lamellipodia protrusion by activating the WAVE2 regulatory complex.". Mol Cell. 2011. PMID 21419341.