VPS28

VPS28
Dynodwyr
Cyfenwau	VPS28, ESCRT-I subunit, VPS28 subunit of ESCRT-I
Dynodwyr allanol	OMIM: 611952 HomoloGene: 69205 GeneCards: VPS28
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0032403 protein-containing complex binding • ubiquitin binding • GO:0001948, GO:0016582 protein binding Cydrannau o'r gell • cytoplasm • cytosol • endosome • bilen • late endosome membrane • Cellbilen • early endosome • endosome membrane • extracellular exosome • ESCRT I complex • host cell Prosesau biolegol • GO:0046795 intracellular transport of virus • positive regulation of ubiquitin-dependent endocytosis • GO:1903364 positive regulation of protein catabolic process • viral budding via host ESCRT complex • GO:0019067 viral life cycle • multivesicular body assembly • endosomal transport • negative regulation of protein ubiquitination • protein transport • ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway • protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway • macroautophagy • GO:0015915 transport • endosome transport via multivesicular body sorting pathway Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	51160	n/a
Ensembl	ENSG00000160948 ENSG00000285339	n/a
UniProt	Q9UK41 Q548N1	n/a
RefSeq (mRNA)	NM_016208 NM_183057	n/a
RefSeq (protein)	NP_057292 NP_898880 NP_057292.1	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn VPS28 yw VPS28 a elwir hefyd yn VPS28, ESCRT-I subunit a Vacuolar protein sorting 28 (Yeast), isoform CRA_a (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 8, band 8q24.3.

Llyfryddiaeth

• "Solution structure of the ESCRT-I complex by small-angle X-ray scattering, EPR, and FRET spectroscopy. ". Proc Natl Acad Sci U S A. 2011. PMID 21596998.
• "YPXL/I is a protein interaction motif recognized by aspergillus PalA and its human homologue, AIP1/Alix. ". Mol Cell Biol. 2003. PMID 12588984.
• "Protein sorting into multivesicular endosomes. ". Curr Opin Cell Biol. 2003. PMID 12892785.
• "Equine infectious anemia virus utilizes host vesicular protein sorting machinery during particle release. ". J Virol. 2003. PMID 12857913.
• "CIIA negatively regulates the Ras-Erk1/2 signaling pathway through inhibiting the Ras-specific GEF activity of SOS1.". J Cell Sci. 2014. PMID 24522193.