VASP

VASP
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1EGX, 1USD, 1USE, 2PAV, 2PBD, 3CHW
Dynodwyr
Cyfenwau	VASP, vasodilator-stimulated phosphoprotein, vasodilator stimulated phosphoprotein
Dynodwyr allanol	OMIM: 601703 HomoloGene: 7592 GeneCards: VASP
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • profilin binding • SH3 domain binding • GO:0001948, GO:0016582 protein binding • actin binding • cadherin binding Cydrannau o'r gell • cell projection • bilen • focal adhesion • bicellular tight junction • filopodium • Cellbilen • cell junction • actin cytoskeleton • extracellular exosome • Cytosgerbwd • lamellipodium membrane • lamellipodium • filopodium membrane • cytoplasm • cytosol Prosesau biolegol • positive regulation of actin filament polymerization • axon guidance • neural tube closure • actin polymerization or depolymerization • protein homotetramerization • actin cytoskeleton organization • cell junction assembly Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	7408	n/a
Ensembl	ENSG00000125753	n/a
UniProt	P50552	n/a
RefSeq (mRNA)	NM_001008736 NM_003370	n/a
RefSeq (protein)	NP_003361	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn VASP yw VASP a elwir hefyd yn Vasodilator-stimulated phosphoprotein a Vasodilator stimulated phosphoprotein (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 19, band 19q13.32.

Llyfryddiaeth

• "Relationship between pharmacokinetics and pharmacodynamics of clopidogrel in patients undergoing percutaneous coronary intervention: comparison between vasodilator-stimulated phosphoprotein phosphorylation assay and multiple electrode aggregometry. ". J Thromb Haemost. 2016. PMID 26576037.
• "The phosphorylation status of VASP at serine 322 can be predictive for aggressiveness of invasive ductal carcinoma. ". Oncotarget. 2015. PMID 26336132.
• "S-nitrosylation of VASP at cysteine 64 mediates the inflammation-stimulated increase in microvascular permeability. ". Am J Physiol Heart Circ Physiol. 2017. PMID 28526707.
• "Vasodilator-Stimulated Phosphoprotein (VASP) depletion from breast cancer MDA-MB-231 cells inhibits tumor spheroid invasion through downregulation of Migfilin, β-catenin and urokinase-plasminogen activator (uPA). ". Exp Cell Res. 2017. PMID 28209486.
• "Vasodilator-Stimulated Phosphoprotein Activity Is Required for Coxiella burnetii Growth in Human Macrophages.". PLoS Pathog. 2016. PMID 27711191.