VAPA

VAPA
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2RR3
Dynodwyr
Cyfenwau	VAPA, VAP-33, VAP-A, VAP33, hVAP-33, VAMP associated protein A, VAMP-A
Dynodwyr allanol	OMIM: 605703 HomoloGene: 37824 GeneCards: VAPA
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • protein domain specific binding • microtubule binding • signal transducer activity • GO:0001948, GO:0016582 protein binding • protein heterodimerization activity • cadherin binding • FFAT motif binding Cydrannau o'r gell • integral component of membrane • fesigl • endoplasmic reticulum membrane • bilen • microtubule cytoskeleton • Reticwlwm endoplasmig • perinuclear region of cytoplasm • endoplasmic reticulum exit site • cell junction • bicellular tight junction • Golgi membrane • nuclear membrane • cnewyllyn cell • Cellbilen • azurophil granule membrane Prosesau biolegol • COPII-coated vesicle budding • marwolaeth celloedd • membrane fusion • protein folding in endoplasmic reticulum • sphingolipid biosynthetic process • endoplasmic reticulum organization • positive regulation by host of viral genome replication • endoplasmic reticulum to Golgi vesicle-mediated transport • positive regulation of I-kappaB kinase/NF-kappaB signaling • protein localization to endoplasmic reticulum • negative regulation by host of viral genome replication • neuron projection development • GO:0072468 signal transduction • neutrophil degranulation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	9218	n/a
Ensembl	ENSG00000101558	n/a
UniProt	Q9P0L0	n/a
RefSeq (mRNA)	NM_003574 NM_194434	n/a
RefSeq (protein)	NP_003565 NP_919415	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn VAPA yw VAPA a elwir hefyd yn VAMP associated protein A (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 18, band 18p11.22.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn VAPA.

• VAP-A
• VAP33
• VAP-33
• hVAP-33

Llyfryddiaeth

• "Sterol liganding of OSBP-related proteins (ORPs) regulates the subcellular distribution of ORP-VAPA complexes and their impacts on organelle structure. ". Steroids. 2015. PMID 25681634.
• "Phosphoregulation of the ceramide transport protein CERT at serine 315 in the interaction with VAMP-associated protein (VAP) for inter-organelle trafficking of ceramide in mammalian cells. ". J Biol Chem. 2014. PMID 24569996.
• "Association between polymorphisms in the vesicle-associated membrane protein-associated protein A (VAPA) gene on chromosome 18p and bipolar disorder. ". J Neural Transm (Vienna). 2008. PMID 18665321.
• "Endosome-ER Contacts Control Actin Nucleation and Retromer Function through VAP-Dependent Regulation of PI4P. ". Cell. 2016. PMID 27419871.
• "CARTS biogenesis requires VAP-lipid transfer protein complexes functioning at the endoplasmic reticulum-Golgi interface.". Mol Biol Cell. 2015. PMID 26490117.