VAMP8

VAMP8
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 4WY4
Dynodwyr
Cyfenwau	VAMP8, EDB, VAMP-8, vesicle associated membrane protein 8
Dynodwyr allanol	OMIM: 603177 HomoloGene: 37846 GeneCards: VAMP8
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • SNAP receptor activity • GO:0001948, GO:0016582 protein binding • chloride channel inhibitor activity • SNARE binding Cydrannau o'r gell • cytoplasm • integral component of membrane • recycling endosome • fesigl • cytosol • endosome • early endosome membrane • bilen • secretory granule membrane • late endosome membrane • Cellbilen • mucin granule • lysosomal membrane • SNARE complex • early endosome • perinuclear region of cytoplasm • lysosome • extracellular exosome • clathrin-coated vesicle membrane • phagocytic vesicle membrane • azurophil granule membrane • specific granule membrane • recycling endosome membrane • tertiary granule membrane • synaptic vesicle Prosesau biolegol • post-Golgi vesicle-mediated transport • autophagy • GO:0000046 autophagosome maturation • negative regulation of secretion by cell • protein transport • viral entry into host cell • vesicle fusion • eosinophil degranulation • vesicle-mediated transport • mucus secretion • regulation of protein localization to plasma membrane • positive regulation of histamine secretion by mast cell • antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent • autophagosome membrane docking • neutrophil degranulation • membrane organization • regulation of molecular function • GO:0015915 transport Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	8673	n/a
Ensembl	ENSG00000118640	n/a
UniProt	Q9BV40	n/a
RefSeq (mRNA)	NM_003761	n/a
RefSeq (protein)	NP_003752	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn VAMP8 yw VAMP8 a elwir hefyd yn Vesicle associated membrane protein 8 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 2, band 2p11.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn VAMP8.

• EDB
• VAMP-8

Llyfryddiaeth

• "[Association of the polymorphism of synaptobrevins/vesicle-associated membrane proteins 8 gene with coronary heart disease in Chinese Han population]. ". Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2010. PMID 20533276.
• "Role of VAMP8/endobrevin in constitutive exocytotic pathway in HeLa cells. ". Cell Struct Funct. 2009. PMID 19738360.
• "No association of VAMP8 gene polymorphisms with glioma in a Chinese Han population. ". Int J Clin Exp Pathol. 2015. PMID 26191281.
• "VAMP8-dependent fusion of recycling endosomes with the plasma membrane facilitates T lymphocyte cytotoxicity. ". J Cell Biol. 2015. PMID 26124288.
• "VAMP8 facilitates cellular proliferation and temozolomide resistance in human glioma cells.". Neuro Oncol. 2015. PMID 25209430.