VAMP7

VAMP7
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	2DMW
Dynodwyr
Cyfenwau	VAMP7, SYBL1, TI-VAMP, TIVAMP, VAMP-7, vesicle associated membrane protein 7
Dynodwyr allanol	OMIM: 300053 HomoloGene: 4121 GeneCards: VAMP7
Patrwm RNA pattern
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• SNARE binding; • SNAP receptor activity; • syntaxin binding; • GO:0001948, GO:0016582 protein binding;
Cydrannau o'r gell	• extracellular exosome; • transport vesicle; • pseudopodium; • cytoplasm; • transport vesicle membrane; • synapse; • integral component of membrane; • trans-Golgi network; • azurophil granule membrane; • Golgi apparatus; • cell junction; • platelet alpha granule; • intracellular membrane-bounded organelle; • lamellipodium; • apical part of cell; • neuron projection; • bilen; • cell surface; • phagocytic vesicle membrane; • Reticwlwm endoplasmig; • perinuclear region of cytoplasm; • endoplasmic reticulum membrane; • secretory granule; • secretory granule membrane; • lysosome; • GO:0016023 cytoplasmic vesicle; • late endosome membrane; • endosome; • phagocytic vesicle; • Cellbilen; • lysosomal membrane; • SNARE complex; • clathrin-coated vesicle membrane; • synaptic vesicle; • integral component of synaptic vesicle membrane; • hippocampal mossy fiber to CA3 synapse;
Prosesau biolegol	• GO:0000046 autophagosome maturation; • vesicle transport along microtubule; • vesicle fusion with Golgi apparatus; • Golgi to plasma membrane protein transport; • positive regulation of histamine secretion by mast cell; • SNARE complex assembly; • calcium-ion regulated exocytosis; • triglyceride transport; • endoplasmic reticulum to Golgi vesicle-mediated transport; • post-Golgi vesicle-mediated transport; • regulation of protein targeting to vacuolar membrane; • exocytosis; • natural killer cell degranulation; • phagocytosis, engulfment; • protein transport; • endosome to lysosome transport; • positive regulation of dendrite morphogenesis; • vesicle fusion; • vesicle-mediated transport; • neutrophil degranulation; • eosinophil degranulation; • endocytosis; • membrane organization; • GO:0015915 transport;
	Sources:Amigo / QuickGO
Orthologau
	6845
	n/a
	ENSG00000124333
	n/a
	P51809
	n/a
	NM_001145149; NM_001185183; NM_005638
	n/a
	NP_001138621; NP_001172112; NP_005629
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn VAMP7 yw VAMP7 a elwir hefyd yn Vesicle associated membrane protein 7 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom X dynol, band Xq28 and Yq12.^[2]

Cyfystyron[golygu | golygu cod]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn VAMP7.

SYBL1
TIVAMP
VAMP-7
TI-VAMP

Llyfryddiaeth[golygu | golygu cod]

"Alternative splicing of the human gene SYBL1 modulates protein domain architecture of Longin VAMP7/TI-VAMP, showing both non-SNARE and synaptobrevin-like isoforms. ". BMC Mol Biol. 2011. PMID 21609427.
"The longin SNARE VAMP7/TI-VAMP adopts a closed conformation. ". J Biol Chem. 2010. PMID 20378544.
"Increased activity of the vesicular soluble N-ethylmaleimide-sensitive factor attachment protein receptor TI-VAMP/VAMP7 by tyrosine phosphorylation in the Longin domain. ". J Biol Chem. 2013. PMID 23471971.
"Endocytic SNAREs are involved in optimal Coxiella burnetii vacuole development. ". Cell Microbiol. 2013. PMID 23217169.
"ATP is released from autophagic vesicles to the extracellular space in a VAMP7-dependent manner.". Autophagy. 2012. PMID 22951367.

Cyfeiriadau[golygu | golygu cod]

[1] "Human PubMed Reference:".

[2] VAMP7 - Cronfa NCBI

[1]

[2]