UTRN

UTRN
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1BHD, 1QAG,%%s1BHD, 1QAG
Dynodwyr
Cyfenwau	UTRN, DMDL, DRP, DRP1, utrophin
Dynodwyr allanol	OMIM: 128240 HomoloGene: 21398 GeneCards: UTRN
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • vinculin binding • zinc ion binding • metal ion binding • integrin binding • actin filament binding • GO:0001948, GO:0016582 protein binding • actin binding • protein kinase binding Cydrannau o'r gell • cytoplasm • postsynaptic membrane • contractile ring • bilen • filopodium • growth cone • neuromuscular junction • Cellbilen • synapse • dystrophin-associated glycoprotein complex • nucleoplasm • cell junction • cortical actin cytoskeleton • sarcolemma • extracellular exosome • Cytosgerbwd • filopodium membrane • GO:0009327 protein-containing complex Prosesau biolegol • muscle contraction • positive regulation of cell-matrix adhesion • muscle organ development • neuromuscular junction development • regulation of sodium ion transmembrane transporter activity • response to denervation involved in regulation of muscle adaptation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	7402	n/a
Ensembl	ENSG00000152818	n/a
UniProt	P46939 Q5T097	n/a
RefSeq (mRNA)	NM_007124 NM_001375323	n/a
RefSeq (protein)	NP_009055 NP_001362252	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn UTRN yw UTRN a elwir hefyd yn Utrophin (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 6, band 6q24.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn UTRN.

• DRP
• DMDL
• DRP1

Llyfryddiaeth

• "Inhibition of Human Glioma Cell Proliferation Caused by Knockdown of Utrophin Using a Lentivirus-Mediated System. ". Cancer Biother Radiopharm. 2016. PMID 27183436.
• "Inhibition of muscle fibrosis results in increases in both utrophin levels and the number of revertant myofibers in Duchenne muscular dystrophy. ". Oncotarget. 2015. PMID 26015394.
• "Mitochondrial dynamics regulates hypoxia-induced migration and antineoplastic activity of cisplatin in breast cancer cells. ". Int J Oncol. 2015. PMID 25434519.
• "The actin binding affinity of the utrophin tandem calponin-homology domain is primarily determined by its N-terminal domain. ". Biochemistry. 2014. PMID 24628267.
• "Autophagy-mediated turnover of dynamin-related protein 1.". BMC Neurosci. 2013. PMID 23937156.