USP2

USP2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2HD5, 2IBI, 3NHE, 3V6C, 3V6E
Dynodwyr
Cyfenwau	USP2, UBP41, USP9, ubiquitin specific peptidase 2
Dynodwyr allanol	OMIM: 604725 HomoloGene: 3098 GeneCards: USP2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • cysteine-type peptidase activity • metal ion binding • GO:0070122 peptidase activity • GO:0001948, GO:0016582 protein binding • identical protein binding • cysteine-type endopeptidase activity • hydrolase activity • ubiquitin protein ligase binding • cyclin binding • thiol-dependent deubiquitinase Cydrannau o'r gell • cytoplasm • centrosome • cell cortex • perinuclear region of cytoplasm • cnewyllyn cell • nucleoplasm • bilen Prosesau biolegol • ubiquitin-dependent protein catabolic process • proses rythmig • muscle organ development • protein stabilization • positive regulation of mitotic cell cycle • GO:1901227 negative regulation of transcription by RNA polymerase II • circadian regulation of gene expression • proteolysis • circadian behavior • cell cycle • entrainment of circadian clock by photoperiod • locomotor rhythm • protein deubiquitination Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	9099	n/a
Ensembl	ENSG00000036672	n/a
UniProt	O75604	n/a
RefSeq (mRNA)	NM_001243759 NM_004205 NM_171997	n/a
RefSeq (protein)	NP_001230688 NP_004196 NP_741994	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn USP2 yw USP2 a elwir hefyd yn Ubiquitin specific peptidase 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 11, band 11q23.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn USP2.

• USP9
• UBP41

Llyfryddiaeth

• "USP2a alters chemotherapeutic response by modulating redox. ". Cell Death Dis. 2013. PMID 24071644.
• "Up-regulation of USP2a and FASN in gliomas correlates strongly with glioma grade. ". J Clin Neurosci. 2013. PMID 23416128.
• "Ubiquitin-specific peptidase 2 as a potential link between microRNA-125b and psoriasis. ". Br J Dermatol. 2017. PMID 27479112.
• "Assess the expression of ubiquitin specific protease USP2a for bladder cancer diagnosis. ". BMC Urol. 2015. PMID 26250800.
• "USP2 promotes cell migration and invasion in triple negative breast cancer cell lines.". Tumour Biol. 2015. PMID 25687182.