UPP1

UPP1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 3EUE, 3EUF, 3NBQ
Dynodwyr
Cyfenwau	UPP1, UDRPASE, UP, UPASE, UPP, uridine phosphorylase 1
Dynodwyr allanol	OMIM: 191730 HomoloGene: 2524 GeneCards: UPP1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • transferase activity • catalytic activity • pentosyltransferase activity • glycosyltransferase activity • uridine phosphorylase activity Cydrannau o'r gell • cytoplasm • cytosol • cnewyllyn cell • nucleoplasm Prosesau biolegol • pyrimidine nucleoside salvage • pyrimidine nucleotide metabolic process • nucleoside metabolic process • uridine metabolic process • nucleotide catabolic process • cellular response to glucose starvation • nucleobase-containing compound metabolic process • pyrimidine nucleoside catabolic process • UMP salvage • uridine catabolic process Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	7378	n/a
Ensembl	ENSG00000183696	n/a
UniProt	Q16831	n/a
RefSeq (mRNA)	NM_001287426 NM_001287428 NM_001287429 NM_001287430 NM_003364 NM_181597 NM_001362774	n/a
RefSeq (protein)	NP_001274355 NP_001274357 NP_001274358 NP_001274359 NP_003355 NP_001349703	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn UPP1 yw UPP1 a elwir hefyd yn Uridine phosphorylase 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 7, band 7p12.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn UPP1.

• UP
• UPP
• UPASE
• UDRPASE

Llyfryddiaeth

• "Homeostatic control of uridine and the role of uridine phosphorylase: a biological and clinical update. ". Biochim Biophys Acta. 2002. PMID 12084455.
• "Expression of uridine and thymidine phosphorylase genes in human breast carcinoma. ". Int J Cancer. 2002. PMID 11807789.
• "Active site conformational dynamics in human uridine phosphorylase 1. ". PLoS One. 2010. PMID 20856879.
• "Implications of the structure of human uridine phosphorylase 1 on the development of novel inhibitors for improving the therapeutic window of fluoropyrimidine chemotherapy. ". BMC Struct Biol. 2009. PMID 19291308.
• "Uridine phosphorylase is a potential prognostic factor in patients with oral squamous cell carcinoma.". Cancer. 2002. PMID 12115385.