UPF2

UPF2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1UW4, 2WJV, 4CEK, 4CEM
Dynodwyr
Cyfenwau	UPF2, HRENT2, smg-3, UPF2 regulator of nonsense transcripts homolog (yeast), regulator of nonsense mediated mRNA decay, UPF2 regulator of nonsense mediated mRNA decay
Dynodwyr allanol	OMIM: 605529 HomoloGene: 6101 GeneCards: UPF2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • telomeric DNA binding • RNA binding Cydrannau o'r gell • cytoplasm • perinuclear region of cytoplasm • exon-exon junction complex • cnewyllyn cell • cytosol • polysome • cytoplasmic ribonucleoprotein granule Prosesau biolegol • liver development • nuclear-transcribed mRNA catabolic process, nonsense-mediated decay • mRNA export from nucleus • animal organ regeneration Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	26019	n/a
Ensembl	ENSG00000151461	n/a
UniProt	Q9HAU5	n/a
RefSeq (mRNA)	NM_015542 NM_080599	n/a
RefSeq (protein)	NP_056357 NP_542166	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn UPF2 yw UPF2 a elwir hefyd yn UPF2, regulator of nonsense mediated mRNA decay (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 10, band 10p14.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn UPF2.

• HUPF2
• RENT2
• smg-3

Llyfryddiaeth

• "Unusual bipartite mode of interaction between the nonsense-mediated decay factors, UPF1 and UPF2. ". EMBO J. 2009. PMID 19556969.
• "Results of the determination of serum markers in patients with malignant melanoma. ". Coll Antropol. 2007. PMID 17469741.
• "Structural and functional analysis of the three MIF4G domains of nonsense-mediated decay factor UPF2. ". Nucleic Acids Res. 2014. PMID 24271394.
• "hUPF2 silencing identifies physiologic substrates of mammalian nonsense-mediated mRNA decay. ". Mol Cell Biol. 2006. PMID 16449641.
• "Human nonsense-mediated mRNA decay factor UPF2 interacts directly with eRF3 and the SURF complex.". Nucleic Acids Res. 2016. PMID 26740584.