UBE2V2

UBE2V2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1J74, 1J7D, 1ZGU, 3VON, 4NR3, 4NRG, 4NRI, 4ONL, 4ONM, 4ONN, 4ORH, 5AIT
Dynodwyr
Cyfenwau	UBE2V2, DDVIT1, DDVit-1, EDAF-1, EDPF-1, EDPF1, MMS2, UEV-2, UEV2, ubiquitin conjugating enzyme E2 V2
Dynodwyr allanol	OMIM: 603001 HomoloGene: 55739 GeneCards: UBE2V2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:1904264, GO:1904822, GO:0090622, GO:0090302 ubiquitin protein ligase activity • GO:0001948, GO:0016582 protein binding • ubiquitin conjugating enzyme activity • ubiquitin protein ligase binding Cydrannau o'r gell • cytoplasm • UBC13-MMS2 complex • extracellular exosome • cnewyllyn cell • nucleoplasm Prosesau biolegol • GO:1904089 negative regulation of neuron apoptotic process • postreplication repair • protein K63-linked ubiquitination • regulation of DNA repair • DNA double-strand break processing • GO:1900404 positive regulation of DNA repair • protein polyubiquitination • global genome nucleotide-excision repair • protein ubiquitination • error-free postreplication DNA repair • positive regulation of neuron projection development • cell population proliferation • double-strand break repair via nonhomologous end joining • positive regulation of proteasomal ubiquitin-dependent protein catabolic process • positive regulation of synapse assembly Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	7336	n/a
Ensembl	ENSG00000169139	n/a
UniProt	Q15819	n/a
RefSeq (mRNA)	NM_003350	n/a
RefSeq (protein)	NP_003341	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn UBE2V2 yw UBE2V2 a elwir hefyd yn Ubiquitin conjugating enzyme E2 V2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 8, band 8q11.21.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn UBE2V2.

• MMS2
• UEV2
• EDPF1
• UEV-2
• DDVIT1
• EDAF-1
• EDPF-1
• DDVit-1

Llyfryddiaeth

• "Molecular cloning of a 1alpha,25-dihydroxyvitamin D3-inducible transcript (DDVit 1) in human blood monocytes. ". Biochem Biophys Res Commun. 1997. PMID 9199207.
• "Catalytic proficiency of ubiquitin conjugation enzymes: balancing pK(a) suppression, entropy, and electrostatics. ". J Am Chem Soc. 2010. PMID 21114314.
• "[Roles of hMMS2 gene in reversing the oxaliplatin tolerance of human colon carcinoma cells]. ". Yi Chuan. 2014. PMID 24846979.
• "Main chain and side chain dynamics of the ubiquitin conjugating enzyme variant human Mms2 in the free and ubiquitin-bound States. ". Biochemistry. 2005. PMID 15952783.
• "UBE2V2 (MMS2) is not required for effective immunoglobulin gene conversion or DNA damage tolerance in DT40.". DNA Repair (Amst). 2005. PMID 15725630.