UBE2K

UBE2K
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1YLA, 2O25, 3E46, 3F92, 3K9O, 3K9P, 5DFL
Dynodwyr
Cyfenwau	UBE2K, E2-25K, HIP2, HYPG, LIG, UBC1, ubiquitin conjugating enzyme E2 K
Dynodwyr allanol	OMIM: 602846 HomoloGene: 3903 GeneCards: UBE2K
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0050372 ubiquitin-protein transferase activity • transferase activity • nucleotide binding • ubiquitin-ubiquitin ligase activity • GO:0001948, GO:0016582 protein binding • ATP binding • ubiquitin protein ligase binding • ubiquitin conjugating enzyme activity Cydrannau o'r gell • cytoplasm • filopodium tip • cnewyllyn cell • cytosol Prosesau biolegol • protein K48-linked ubiquitination • positive regulation of type I interferon-mediated signaling pathway • intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress • free ubiquitin chain polymerization • positive regulation of peptidyl-threonine phosphorylation • ubiquitin-dependent protein catabolic process • cellular response to interferon-beta • proteasome-mediated ubiquitin-dependent protein catabolic process • regulation of proteasomal ubiquitin-dependent protein catabolic process • protein ubiquitination Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	3093	n/a
Ensembl	ENSG00000078140	n/a
UniProt	P61086	n/a
RefSeq (mRNA)	NM_005339 NM_001111112 NM_001111113 NM_001312646 NM_001312647 NM_001312648 NM_032733	n/a
RefSeq (protein)	NP_001104582 NP_001104583 NP_001299575 NP_001299576 NP_001299577 NP_005330	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn UBE2K yw UBE2K a elwir hefyd yn Ubiquitin conjugating enzyme E2 K (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 4, band 4p14.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn UBE2K.

• LIG
• HIP2
• HYPG
• UBC1
• E2-25K

Llyfryddiaeth

• "The molecular basis of lysine 48 ubiquitin chain synthesis by Ube2K. ". Sci Rep. 2015. PMID 26592444.
• "Ubiquitin-conjugating enzyme E2-25K increases aggregate formation and cell death in polyglutamine diseases. ". Mol Cell Neurosci. 2007. PMID 17092742.
• "Regulation of macrophage-specific gene expression by degenerated lipoproteins. ". Electrophoresis. 2000. PMID 10675012.
• "Blockade of Deubiquitylating Enzyme USP1 Inhibits DNA Repair and Triggers Apoptosis in Multiple Myeloma Cells. ". Clin Cancer Res. 2017. PMID 28270494.
• "The HIP2~ubiquitin conjugate forms a non-compact monomeric thioester during di-ubiquitin synthesis.". PLoS One. 2015. PMID 25799589.