UBE2E1

UBE2E1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1XR9, 3BZH, 4JJQ
Dynodwyr
Cyfenwau	UBE2E1, UBCH6, ubiquitin conjugating enzyme E2 E1
Dynodwyr allanol	OMIM: 602916 HomoloGene: 84372 GeneCards: UBE2E1
EC number	2.3.2.24
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • transferase activity • nucleotide binding • ISG15 transferase activity • GO:0050372 ubiquitin-protein transferase activity • GO:0001948, GO:0016582 protein binding • ATP binding • ubiquitin conjugating enzyme activity Cydrannau o'r gell • cytosol • ubiquitin ligase complex • nucleoplasm • cnewyllyn cell Prosesau biolegol • histone monoubiquitination • ubiquitin-dependent protein catabolic process • protein polyubiquitination • protein K48-linked ubiquitination • ISG15-protein conjugation • anaphase-promoting complex-dependent catabolic process • histone H2B ubiquitination • protein ubiquitination • regulation of mitotic cell cycle phase transition Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	7324	n/a
Ensembl	ENSG00000170142	n/a
UniProt	P51965	n/a
RefSeq (mRNA)	NM_001202476 NM_003341 NM_182666	n/a
RefSeq (protein)	NP_001189405 NP_003332 NP_872607 NP_003332.1	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn UBE2E1 yw UBE2E1 a elwir hefyd yn Ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, yeast), isoform CRA_a ac Ubiquitin-conjugating enzyme E2 E1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 3, band 3p24.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn UBE2E1.

• UBCH6

Llyfryddiaeth

• "UbE2E1/UBCH6 Is a Critical in VivoE2 for the PRC1-catalyzed Ubiquitination of H2A at Lys-119. ". J Biol Chem. 2017. PMID 28073915.
• "A key lysine residue in the AXH domain of ataxin-1 is essential for its ubiquitylation. ". Biochim Biophys Acta. 2015. PMID 25641559.
• "Microarray-based analysis and clinical validation identify ubiquitin-conjugating enzyme E2E1 (UBE2E1) as a prognostic factor in acute myeloid leukemia. ". J Hematol Oncol. 2016. PMID 27855695.
• "The structure and conformation of Lys63-linked tetraubiquitin. ". J Mol Biol. 2009. PMID 19664638.
• "Mechanisms underlying ubiquitination.". Annu Rev Biochem. 2001. PMID 11395416.