UBE2C

UBE2C
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1I7K, 4YII, 5A31
Dynodwyr
Cyfenwau	UBE2C, UBCH10, dJ447F3.2, ubiquitin conjugating enzyme E2 C
Dynodwyr allanol	OMIM: 605574 HomoloGene: 5096 GeneCards: UBE2C
EC number	2.3.2.24
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • transferase activity • nucleotide binding • GO:1904264, GO:1904822, GO:0090622, GO:0090302 ubiquitin protein ligase activity • GO:0050372 ubiquitin-protein transferase activity • GO:0001948, GO:0016582 protein binding • ATP binding • ubiquitin conjugating enzyme activity • ubiquitin protein ligase binding • ubiquitin-like protein ligase binding Cydrannau o'r gell • cytoplasm • nucleoplasm • anaphase-promoting complex • cytosol • Cellbilen • ubiquitin ligase complex • cnewyllyn cell Prosesau biolegol • free ubiquitin chain polymerization • ubiquitin-dependent protein catabolic process • exit from mitosis • positive regulation of exit from mitosis • protein K11-linked ubiquitination • Cellraniad • protein K48-linked ubiquitination • regulation of mitotic metaphase/anaphase transition • cell cycle • anaphase-promoting complex-dependent catabolic process • GO:0090623, GO:1903835, GO:0007092, GO:0051488, GO:0051487 positive regulation of ubiquitin protein ligase activity • protein ubiquitination • regulation of mitotic cell cycle phase transition Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	11065	n/a
Ensembl	ENSG00000175063	n/a
UniProt	O00762 Q5TZN3	n/a
RefSeq (mRNA)	NM_001281741 NM_001281742 NM_007019 NM_181799 NM_181800 NM_181801 NM_181802 NM_181803	n/a
RefSeq (protein)	NP_001268670 NP_001268671 NP_008950 NP_861515 NP_861516 NP_861517 NP_008950.1	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn UBE2C yw UBE2C a elwir hefyd yn Ubiquitin conjugating enzyme E2 C ac UBE2C protein (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 20, band 20q13.12.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn UBE2C.

• UBCH10
• dJ447F3.2

Llyfryddiaeth

• "UbcH10 expression can predict prognosis and sensitivity to the antineoplastic treatment for colorectal cancer patients. ". Mol Carcinog. 2016. PMID 25917796.
• "Ubiquitin-conjugating enzyme E2C regulates apoptosis-dependent tumor progression of non-small cell lung cancer via ERK pathway. ". Med Oncol. 2015. PMID 25832867.
• "Transcript Levels of Androgen Receptor Variant 7 and Ubiquitin-Conjugating Enzyme 2C in Hormone Sensitive Prostate Cancer and Castration-Resistant Prostate Cancer. ". Prostate. 2017. PMID 27550197.
• "Ubiquitin-conjugating enzyme UbcH10 promotes gastric cancer growth and is a potential biomarker for gastric cancer. ". Oncol Rep. 2016. PMID 27349176.
• "UbcH10 overexpression is less pronounced in older colorectal cancer patients.". Int J Colorectal Dis. 2016. PMID 26744065.