UBA52

UBA52
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2LJ5, 2MBH, 2MJB, 2MUR, 2RSU, 4HJK, 4JIO, 4P4H, 4PIG, 4PIH, 4PIJ, 4RF0, 4RF1, 4S1Z, 4UG0, 4V6X, 5AJ0, 4UJD, 4D67, 4UJC, 3J7P, 3J7Q, 4XKL, 3J92, 4D5Y, 3J7O, 3J7R, 3PHD, 2KOX, 4UJE, 5A5B, 2N3V, 2N3U, 2N3W, 2NBD, 2NBE, 3VDZ, 5HPS, 3I3T, 5HPT, 5JBV, 5HPL, 5HPK, 5J8P
Dynodwyr
Cyfenwau	UBA52, CEP52, HUBCEP52, L40, RPL40, Ubiquitin A-52 residue ribosomal protein fusion product 1
Dynodwyr allanol	OMIM: 191321 HomoloGene: 68307 GeneCards: UBA52
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • structural constituent of ribosome • GO:0001948, GO:0016582 protein binding • protein tag • ubiquitin protein ligase binding Cydrannau o'r gell • cytoplasm • endocytic vesicle membrane • cnewyllyn cell • ribosom • extracellular exosome • endosome membrane • lysosomal membrane • extracellular space • nucleoplasm • mitochondrial outer membrane • Reticwlwm endoplasmig • cytosol • Cellbilen • endoplasmic reticulum quality control compartment • fesigl • endoplasmic reticulum membrane • host cell • cytosolic large ribosomal subunit • cytosolic small ribosomal subunit • synapse Prosesau biolegol • DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest • negative regulation of epidermal growth factor receptor signaling pathway • interstrand cross-link repair • nucleotide-excision repair, DNA damage recognition • positive regulation of canonical Wnt signaling pathway • tumor necrosis factor-mediated signaling pathway • regulation of type I interferon production • TRIF-dependent toll-like receptor signaling pathway • Fc-epsilon receptor signaling pathway • endosomal transport • global genome nucleotide-excision repair • NIK/NF-kappaB signaling • G2/M transition of mitotic cell cycle • stress-activated MAPK cascade • transforming growth factor beta receptor signaling pathway • macroautophagy • negative regulation of canonical Wnt signaling pathway • nucleotide-excision repair, DNA gap filling • viral transcription • error-free translesion synthesis • regulation of tumor necrosis factor-mediated signaling pathway • stimulatory C-type lectin receptor signaling pathway • negative regulation of transforming growth factor beta receptor signaling pathway • SRP-dependent cotranslational protein targeting to membrane • JNK cascade • regulation of transcription from RNA polymerase II promoter in response to hypoxia • nucleotide-excision repair, DNA incision • I-kappaB kinase/NF-kappaB signaling • innate immune response • Notch signaling pathway • regulation of mRNA stability • protein polyubiquitination • negative regulation of apoptotic process • GO:1901227 negative regulation of transcription by RNA polymerase II • virion assembly • positive regulation of NF-kappaB transcription factor activity • anaphase-promoting complex-dependent catabolic process • negative regulation of type I interferon production • nuclear-transcribed mRNA catabolic process, nonsense-mediated decay • nucleotide-binding oligomerization domain containing signaling pathway • GO:0046795 intracellular transport of virus • GO:0019067 viral life cycle • MyD88-dependent toll-like receptor signaling pathway • error-prone translesion synthesis • MAPK cascade • fibroblast growth factor receptor signaling pathway • cludo transmembrane rhwng ïonau • glycogen biosynthetic process • positive regulation of apoptotic process • translational initiation • positive regulation of I-kappaB kinase/NF-kappaB signaling • translesion synthesis • transcription-coupled nucleotide-excision repair • T cell receptor signaling pathway • MyD88-independent toll-like receptor signaling pathway • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II • positive regulation of epidermal growth factor receptor signaling pathway • proteasome-mediated ubiquitin-dependent protein catabolic process • regulation of signal transduction by p53 class mediator • Wnt signaling pathway, planar cell polarity pathway • nucleotide-excision repair, DNA incision, 5'-to lesion • protein biosynthesis • nucleotide-excision repair, preincision complex assembly • rRNA processing • Wnt signaling pathway • ERBB2 signaling pathway • nucleotide-excision repair, DNA duplex unwinding • protein folding • negative regulation of G2/M transition of mitotic cell cycle • protein ubiquitination • protein deubiquitination • SCF-dependent proteasomal ubiquitin-dependent protein catabolic process • entry of bacterium into host cell • transmembrane transport • regulation of necroptotic process • membrane organization • endoplasmic reticulum mannose trimming • cellular iron ion homeostasis • regulation of hematopoietic stem cell differentiation • protein targeting to peroxisome • cytokine-mediated signaling pathway • modification-dependent protein catabolic process • interleukin-1-mediated signaling pathway • response to insecticide Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	7311	n/a
Ensembl	ENSG00000221983	n/a
UniProt	P62987	n/a
RefSeq (mRNA)	NM_001033930 NM_003333 NM_001321017 NM_001321018 NM_001321019 NM_001321020 NM_001321021 NM_001321022	n/a
RefSeq (protein)	NP_001029102 NP_001307946 NP_001307947 NP_001307948 NP_001307949 NP_001307950 NP_001307951 NP_003324	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn UBA52 yw UBA52 a elwir hefyd yn Ubiquitin A-52 residue ribosomal protein fusion product 1 ac Ubiquitin-60S ribosomal protein L40 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 19, band 19p13.11.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn UBA52.

• L40
• CEP52
• RPL40
• HUBCEP52

Llyfryddiaeth

• "Localization of the human UBA52 ubiquitin fusion gene to chromosome band 19p13.1-p12. ". Genomics. 1994. PMID 8188300.
• "Gene synthesis, expression, and processing of human ubiquitin carboxyl extension proteins. ". J Biol Chem. 1989. PMID 2537304.
• "cDNA encoding a human homolog of yeast ubiquitin 1. ". Nucleic Acids Res. 1987. PMID 3037496.
• "New roles for ubiquitin in the assembly and function of neuronal circuits. ". Neuron. 2002. PMID 12367500.
• "Ubiquitin junction, what's your function?". Genome Biol. 2001. PMID 11597332.