TXN2

TXN2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1UVZ, 1W4V, 1W89
Dynodwyr
Cyfenwau	TXN2, MT-TRX, MTRX, TRX2, COXPD29, thioredoxin 2, TXN
Dynodwyr allanol	OMIM: 609063 HomoloGene: 40849 GeneCards: TXN2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • peptide-methionine (S)-S-oxide reductase activity • peptide-methionine (R)-S-oxide reductase activity • GO:0001948, GO:0016582 protein binding • protein-disulfide reductase activity • GO:0032403 protein-containing complex binding Cydrannau o'r gell • nucleolus • mitocondria • mitochondrial matrix • neuronal cell body • dendrite Prosesau biolegol • response to hypoxia • response to hormone • cellular response to nutrient levels • GO:1904578 response to organic cyclic compound • GO:0001306 response to oxidative stress • glycerol ether metabolic process • response to axon injury • response to glucose • cell redox homeostasis • sulfur amino acid catabolic process Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	25828	n/a
Ensembl	n/a	n/a
UniProt	Q99757	n/a
RefSeq (mRNA)	NM_012473	n/a
RefSeq (protein)	NP_036605	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn TXN2 yw TXN2 a elwir hefyd yn Thioredoxin 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 22, band 22q12.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn TXN2.

• TXN
• MTRX
• TRX2
• MT-TRX
• COXPD29

Llyfryddiaeth

• "Genetic polymorphisms in the thioredoxin 2 (TXN2) gene and risk for spina bifida. ". Am J Med Genet A. 2009. PMID 19165900.
• "Human mitochondrial thioredoxin. Involvement in mitochondrial membrane potential and cell death. ". J Biol Chem. 2002. PMID 12080052.
• "Hypoxia inhibits expression and function of mitochondrial thioredoxin 2 to promote pulmonary hypertension. ". Am J Physiol Lung Cell Mol Physiol. 2017. PMID 28130258.
• "Thioredoxin 2 Is a Novel E2-Interacting Protein That Inhibits the Replication of Classical Swine Fever Virus. ". J Virol. 2015. PMID 26041303.
• "A mitochondrial thioredoxin-sensitive mechanism regulates TGF-β-mediated gene expression associated with epithelial-mesenchymal transition.". Biochem Biophys Res Commun. 2014. PMID 24342608.