TSFM

TSFM
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2CP9
Dynodwyr
Cyfenwau	TSFM, EFTS, EFTSMT, Ts translation elongation factor, mitochondrial
Dynodwyr allanol	OMIM: 604723 HomoloGene: 4184 GeneCards: TSFM
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • translation elongation factor activity • RNA binding • GO:0001948, GO:0016582 protein binding Cydrannau o'r gell • mitochondrial matrix • intracellular anatomical structure • mitocondria • cnewyllyn cell Prosesau biolegol • translational elongation • regulation of DNA-templated transcription, elongation • protein biosynthesis • mitochondrial translational elongation • regulation of mitochondrial translation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	10102	n/a
Ensembl	ENSG00000123297	n/a
UniProt	P43897	n/a
RefSeq (mRNA)	NM_005726 NM_001172695 NM_001172696 NM_001172697	n/a
RefSeq (protein)	NP_001166166 NP_001166167 NP_001166168 NP_005717	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn TSFM yw TSFM a elwir hefyd yn Ts translation elongation factor, mitochondrial (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 12, band 12q14.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn TSFM.

• EFTS
• EFTSMT

Llyfryddiaeth

• "Molecular-genetic characterization and rescue of a TSFM mutation causing childhood-onset ataxia and nonobstructive cardiomyopathy. ". Eur J Hum Genet. 2016. PMID 27677415.
• "Distinct clinical phenotypes associated with a mutation in the mitochondrial translation elongation factor EFTs. ". Am J Hum Genet. 2006. PMID 17033963.
• "Mitochondrial EFTs defects in juvenile-onset Leigh disease, ataxia, neuropathy, and optic atrophy. ". Neurology. 2014. PMID 25037205.
• "Mutation in the mitochondrial translation elongation factor EFTs results in severe infantile liver failure. ". J Hepatol. 2012. PMID 21741925.
• "Assignment of the mitochondrial translation elongation factor Ts gene (TSFM) to human chromosome 12 bands q13-->q14 by in situ hybridization and with somatic cell hybrids.". Cytogenet Cell Genet. 2000. PMID 10965106.