TRIP6

TRIP6
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1X61, 2DLO
Dynodwyr
Cyfenwau	TRIP6, OIP-1, OIP1, TRIP-6, TRIP6i2, ZRP-1, thyroid hormone receptor interactor 6
Dynodwyr allanol	OMIM: 602933 HomoloGene: 37757 GeneCards: TRIP6
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • kinase binding • GO:0001948, GO:0016582 protein binding • interleukin-1 receptor binding • metal ion binding • thyroid hormone receptor binding • RNA binding Cydrannau o'r gell • cell junction • Cellbilen • interleukin-1 receptor complex • Cytosgerbwd • cnewyllyn cell • focal adhesion • cytoplasm • cytosol • stress fiber Prosesau biolegol • focal adhesion assembly • cell adhesion • GO:0009373 regulation of transcription, DNA-templated • transcription, DNA-templated • positive regulation of cell migration • positive regulation of NIK/NF-kappaB signaling • GO:0072468 signal transduction Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	7205	n/a
Ensembl	ENSG00000087077	n/a
UniProt	Q15654	n/a
RefSeq (mRNA)	NM_003302	n/a
RefSeq (protein)	NP_003293	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn TRIP6 yw TRIP6 a elwir hefyd yn Thyroid hormone receptor interactor 6 a Thyroid receptor-interacting protein 6 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 7, band 7q22.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn TRIP6.

• OIP1
• OIP-1
• ZRP-1
• TRIP-6
• TRIP6i2

Llyfryddiaeth

• "TRIP6, a novel molecular partner of the MAGI-1 scaffolding molecule, promotes invasiveness. ". FASEB J. 2009. PMID 19017743.
• "ZRP-1 controls Rho GTPase-mediated actin reorganization by localizing at cell-matrix and cell-cell adhesions. ". J Cell Sci. 2007. PMID 17652164.
• "The Zyxin-related protein thyroid receptor interacting protein 6 (TRIP6) is overexpressed in Ewing's sarcoma and promotes migration, invasion and cell growth. ". Biol Cell. 2013. PMID 24033704.
• "Characterization of TRIP6-dependent nasopharyngeal cancer cell migration. ". Tumour Biol. 2013. PMID 23576104.
• "Defining the role of TRIP6 in cell physiology and cancer.". Biol Cell. 2011. PMID 22054418.