TRAPPC4

TRAPPC4
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2J3T, 2JSN, 2ZMV
Dynodwyr
Cyfenwau	TRAPPC4, HSPC172, PTD009, SBDN, SYNBINDIN, TRS23, CGI-104, trafficking protein particle complex 4, NEDESBA, trafficking protein particle complex subunit 4
Dynodwyr allanol	OMIM: 610971 HomoloGene: 105453 GeneCards: TRAPPC4
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding Cydrannau o'r gell • cytosol • Golgi apparatus • synaptic vesicle • synapse • dendrite • Reticwlwm endoplasmig • Golgi stack • Golgi membrane • TRAPP complex Prosesau biolegol • dendrite development • COPII vesicle coating • vesicle-mediated transport • endoplasmic reticulum to Golgi vesicle-mediated transport Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	51399	n/a
Ensembl	ENSG00000280495 ENSG00000196655	n/a
UniProt	Q9Y296	n/a
RefSeq (mRNA)	NM_016146 NM_001318486 NM_001318488 NM_001318489 NM_001318490 NM_001318492 NM_001318494	n/a
RefSeq (protein)	NP_001305415 NP_001305417 NP_001305418 NP_001305419 NP_001305421 NP_001305423 NP_057230	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn TRAPPC4 yw TRAPPC4 a elwir hefyd yn Trafficking protein particle complex 4 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 11, band 11q23.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn TRAPPC4.

• SBDN
• TRS23
• PTD009
• CGI-104
• HSPC172
• SYNBINDIN

Llyfryddiaeth

• "TRAPPC4-ERK2 interaction activates ERK1/2, modulates its nuclear localization and regulates proliferation and apoptosis of colorectal cancer cells. ". PLoS One. 2011. PMID 21826244.
• "Single-cell expression profiling of dopaminergic neurons combined with association analysis identifies pyridoxal kinase as Parkinson's disease gene. ". Ann Neurol. 2009. PMID 20035503.
• "The role of ERK2 in colorectal carcinogenesis is partly regulated by TRAPPC4. ". Mol Carcinog. 2014. PMID 23625650.
• "Crystal structure of human synbindin reveals two conformations of longin domain. ". Biochem Biophys Res Commun. 2009. PMID 18466758.
• "Synbindin in extracellular signal-regulated protein kinase spatial regulation and gastric cancer aggressiveness.". J Natl Cancer Inst. 2013. PMID 24104608.