TRA2B

TRA2B
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2CQC, 2KXN, 2RRA, 2RRB
Dynodwyr
Cyfenwau	TRA2B, Htra2-beta, PPP1R156, SFRS10, SRFS10, TRA2-BETA, TRAN2B, transformer 2 beta homolog (Drosophila), transformer 2 beta homolog
Dynodwyr allanol	OMIM: 602719 HomoloGene: 20965 GeneCards: TRA2B
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • nucleic acid binding • mRNA binding • GO:0001948, GO:0016582 protein binding • poly-purine tract binding • RNA binding • protein domain specific binding • pre-mRNA binding • identical protein binding Cydrannau o'r gell • cnewyllyn cell • nuclear inner membrane • nucleoplasm • spliceosomal complex • ribonucleoprotein complex Prosesau biolegol • RNA splicing, via transesterification reactions • RNA splicing • cerebral cortex regionalization • mRNA processing • negative regulation of mRNA splicing, via spliceosome • embryonic brain development • mRNA splicing, via spliceosome • positive regulation of mRNA splicing, via spliceosome • regulation of alternative mRNA splicing, via spliceosome • regulation of RNA splicing • protein complex oligomerization • cellular response to glucose stimulus Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	6434	n/a
Ensembl	ENSG00000136527	n/a
UniProt	P62995	n/a
RefSeq (mRNA)	NM_001243879 NM_004593	n/a
RefSeq (protein)	NP_001230808 NP_004584	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn TRA2B yw TRA2B a elwir hefyd yn Transformer 2 beta homolog (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 3, band 3q27.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn TRA2B.

• SFRS10
• SRFS10
• TRAN2B
• PPP1R156
• TRA2-BETA
• Htra2-beta

Llyfryddiaeth

• "Characterization of nuclear localization signals (NLSs) and function of NLSs and phosphorylation of serine residues in subcellular and subnuclear localization of transformer-2β (Tra2β). ". J Biol Chem. 2013. PMID 23396973.
• "Ets1 and heat shock factor 1 regulate transcription of the Transformer 2β gene in human colon cancer cells. ". J Gastroenterol. 2013. PMID 23361474.
• "Knocking down the expression of TRA2β inhibits the proliferation and migration of human glioma cells. ". Pathol Res Pract. 2015. PMID 26298634.
• "Prognostic value of transformer 2β expression in prostate cancer. ". Int J Clin Exp Pathol. 2015. PMID 26261585.
• "Transformer 2β (Tra2β/SFRS10) positively regulates the progression of NSCLC via promoting cell proliferation.". J Mol Histol. 2014. PMID 24952301.