TNPO1

TNPO1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1QBK, 2H4M, 2OT8, 2QMR, 2Z5J, 2Z5K, 2Z5M, 2Z5N, 2Z5O, 4FDD, 4FQ3, 4JLQ, 4OO6
Dynodwyr
Cyfenwau	TNPO1, IPO2, KPNB2, MIP, MIP1, TRN, Transportin 1
Dynodwyr allanol	OMIM: 602901 HomoloGene: 5358 GeneCards: TNPO1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • nuclear localization sequence binding • RNA binding Cydrannau o'r gell • cytoplasm • cytosol • nuclear membrane • nuclear periphery • extracellular exosome • cnewyllyn cell • cilium Prosesau biolegol • ribosomal protein import into nucleus • regulation of mRNA stability • protein transport • GO:0022415 viral process • intracellular protein transport • NLS-bearing protein import into nucleus • intraciliary transport involved in cilium assembly • GO:0015915 transport • protein import into nucleus Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	3842	n/a
Ensembl	ENSG00000083312	n/a
UniProt	Q92973	n/a
RefSeq (mRNA)	NM_002270 NM_153188	n/a
RefSeq (protein)	NP_002261 NP_694858 NP_001351221 NP_001351222 NP_001351223 NP_001351224 NP_001351225	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn TNPO1 yw TNPO1 a elwir hefyd yn Transportin-1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 5, band 5q13.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn TNPO1.

• MIP
• TRN
• IPO2
• MIP1
• KPNB2

Llyfryddiaeth

• "Karyopherin-β2 Recognition of a PY-NLS Variant that Lacks the Proline-Tyrosine Motif. ". Structure. 2016. PMID 27618664.
• "Conformational heterogeneity of karyopherin beta2 is segmental. ". Structure. 2007. PMID 17997969.
• "Structural basis for substrate recognition and dissociation by human transportin 1. ". Mol Cell. 2007. PMID 17936704.
• "Nuclear import of hnRNP A1 is mediated by a novel cellular cofactor related to karyopherin-beta. ". J Cell Sci. 1997. PMID 9202393.
• "Transportin: nuclear transport receptor of a novel nuclear protein import pathway.". Exp Cell Res. 1996. PMID 8986607.