TNFSF15

TNFSF15
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2O0O, 2QE3, 2RE9, 2RJK, 2RJL, 3K51, 3MI8
Dynodwyr
Cyfenwau	TNFSF15, TL1, TL1A, VEGI, VEGI192A, Vascular endothelial growth inhibitor, TNLG1B, tumor necrosis factor superfamily member 15, TNF superfamily member 15
Dynodwyr allanol	OMIM: 604052 HomoloGene: 3755 GeneCards: TNFSF15
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • tumor necrosis factor receptor binding • cytokine activity • signaling receptor binding • GO:0001948, GO:0016582 protein binding Cydrannau o'r gell • integral component of membrane • extracellular region • Cellbilen • integral component of plasma membrane • bilen • intracellular anatomical structure • extracellular space Prosesau biolegol • tumor necrosis factor-mediated signaling pathway • activation of cysteine-type endopeptidase activity involved in apoptotic process • activation of NF-kappaB-inducing kinase activity • GO:0046730, GO:0046737, GO:0046738, GO:0046736 immune response • GO:0097285 apoptotic process • GO:0072468 signal transduction • regulation of signaling receptor activity Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	9966	n/a
Ensembl	ENSG00000181634	n/a
UniProt	O95150	n/a
RefSeq (mRNA)	NM_005118 NM_001204344	n/a
RefSeq (protein)	NP_001191273 NP_005109	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn TNFSF15 yw TNFSF15 a elwir hefyd yn TNF superfamily member 15 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 9, band 9q32.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn TNFSF15.

• TL1
• TL1A
• VEGI
• TNLG1B
• VEGI192A

Llyfryddiaeth

• "Genetic analysis of TNFST15 variants in ankylosing spondylitis. ". Int J Clin Exp Pathol. 2015. PMID 26823868.
• "Association of Genetic Variations in TNFSF15 With Acute Anterior Uveitis in Chinese Han. ". Invest Ophthalmol Vis Sci. 2015. PMID 26200500.
• "Protein of Vascular Endothelial Growth Inhibitor 174 Inhibits Epithelial-Mesenchymal Transition in Renal Cell Carcinoma In Vivo. ". Anticancer Res. 2017. PMID 28739718.
• "Diverticulitis and Crohn's disease have distinct but overlapping tumor necrosis superfamily 15 haplotypes. ". J Surg Res. 2017. PMID 28624054.
• "Confounding effects of microbiome on the susceptibility of TNFSF15 to Crohn's disease in the Ryukyu Islands.". Hum Genet. 2017. PMID 28197769.