TNC

TNC
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1TEN, 2RB8, 2RBL
Dynodwyr
Cyfenwau	TNC, 150-225, DFNA56, GMEM, GP, HXB, JI, TN, TN-C, Tenascin C
Dynodwyr allanol	OMIM: 187380 HomoloGene: 55636 GeneCards: TNC
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • syndecan binding • extracellular matrix structural constituent • GO:0001948, GO:0016582 protein binding Cydrannau o'r gell • interstitial matrix • bilen • focal adhesion • GO:0005578 extracellular matrix • basement membrane • extracellular space • endoplasmic reticulum lumen • extracellular region • collagen-containing extracellular matrix • perisynaptic extracellular matrix Prosesau biolegol • cellular response to retinoic acid • negative regulation of cell adhesion • bud outgrowth involved in lung branching • mesenchymal-epithelial cell signaling involved in prostate gland development • response to fibroblast growth factor • response to mechanical stimulus • extracellular matrix organization • wound healing • cellular response to vitamin D • odontogenesis of dentin-containing tooth • GO:1901313 positive regulation of gene expression • cell adhesion • prostate gland epithelium morphogenesis • cellular response to prostaglandin D stimulus • regulation of cell population proliferation • neuromuscular junction development • response to wounding • peripheral nervous system axon regeneration • osteoblast differentiation • positive regulation of cell population proliferation • response to ethanol • neuron projection development • post-translational protein modification Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	3371	n/a
Ensembl	ENSG00000041982	n/a
UniProt	P24821	n/a
RefSeq (mRNA)	NM_002160	n/a
RefSeq (protein)	NP_002151	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn TNC yw TNC a elwir hefyd yn Tenascin C a Tenascin (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 9, band 9q33.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn TNC.

• GP
• JI
• TN
• HXB
• GMEM
• TN-C
• DFNA56
• 150-225

Llyfryddiaeth

• "T/T homozygosity of the tenascin-C gene polymorphism rs2104772 negatively influences exercise-induced angiogenesis. ". PLoS One. 2017. PMID 28384286.
• "Distinct microenvironmental cues stimulate divergent TLR4-mediated signaling pathways in macrophages. ". Sci Signal. 2016. PMID 27577261.
• "Tenascin-C Is Associated with Cored Amyloid-β Plaques in Alzheimer Disease and Pathology Burdened Cognitively Normal Elderly. ". J Neuropathol Exp Neurol. 2016. PMID 27444354.
• "Candidate gene approach identifies six SNPs in tenascin-C (TNC) associated with degenerative rotator cuff tears. ". J Orthop Res. 2017. PMID 27248364.
• "Epidermal growth factor-like repeats of tenascin-C-induced constriction of cerebral arteries via activation of epidermal growth factor receptors in rats.". Brain Res. 2016. PMID 27086972.