TFPI2

TFPI2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1ZR0
Dynodwyr
Cyfenwau	TFPI2, PP5, REF1, TFPI-2, tissue factor pathway inhibitor 2
Dynodwyr allanol	OMIM: 600033 HomoloGene: 38194 GeneCards: TFPI2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • peptidase inhibitor activity • extracellular matrix structural constituent • serine-type endopeptidase inhibitor activity Cydrannau o'r gell • extracellular region • GO:0005578 extracellular matrix • extracellular space Prosesau biolegol • hemostasis • negative regulation of peptidase activity • blood coagulation • negative regulation of endopeptidase activity • cellular response to fluid shear stress Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	7980	n/a
Ensembl	ENSG00000105825	n/a
UniProt	P48307	n/a
RefSeq (mRNA)	NM_006528 NM_001271003 NM_001271004	n/a
RefSeq (protein)	NP_001257932 NP_001257933 NP_006519	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn TFPI2 yw TFPI2 a elwir hefyd yn Tissue factor pathway inhibitor 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 7, band 7q21.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn TFPI2.

• PP5
• REF1
• TFPI-2

Llyfryddiaeth

• "Clinical Significance of Tissue Factor Pathway Inhibitor 2, a Serum Biomarker Candidate for Ovarian Clear Cell Carcinoma. ". PLoS One. 2016. PMID 27798689.
• "Methylation of tissue factor pathway inhibitor 2 as a prognostic biomarker for hepatocellular carcinoma after hepatectomy. ". J Gastroenterol Hepatol. 2016. PMID 26313014.
• "Hypomethylation of tissue factor pathway inhibitor 2 in human placenta of preeclampsia. ". Thromb Res. 2017. PMID 28208084.
• "TFPI-2 expression is decreased in bladder cancer and is related to apoptosis. ". J BUON. 2016. PMID 28039717.
• "Ro 90-7501 inhibits PP5 through a novel, TPR-dependent mechanism.". Biochem Biophys Res Commun. 2017. PMID 27840051.