TEK

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TEK
Protein TEK PDB 1fvr.png
Strwythurau
PDBOrthologau:PDBe RCSB
Dynodwyr
CyfenwauTEK, CD202B, TIE-2, TIE2, VMCM, VMCM1, TEK tyrosine kinase, TEK receptor tyrosine kinase, GLC3E
Dynodwyr allanolOMIM: 600221 MGI: 98664 HomoloGene: 397 GeneCards: TEK
Patrwm RNA pattern
PBB GE TEK 217711 at fs.png

PBB GE TEK 206702 at fs.png
Rhagor o gyfeiriadau
Orthologau
SpeciesBod dynolLlygoden
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_000459
NM_001290077
NM_001290078

NM_001290549
NM_001290551
NM_013690

RefSeq (protein)

NP_000450
NP_001277006
NP_001277007

NP_001277478
NP_001277480
NP_038718

Lleoliad (UCSC)n/aChr : 94.74 – 94.87 Mb
PubMed search[2][3]
Wicidata
Gweld/Golygu Bod dynolGweld/Golygu Llygoden

Protein sy'n cael ei godio yn y corff dynol gan y genyn TEK yw TEK a elwir hefyd yn Angiopoietin-1 receptor a TEK receptor tyrosine kinase (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 9, band 9p21.2.[4]

Cyfystyron[golygu | golygu cod y dudalen]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn TEK.

  • TIE2
  • VMCM
  • GLC3E
  • TIE-2
  • VMCM1
  • CD202B

Llyfryddiaeth[golygu | golygu cod y dudalen]

  • "Enhanced Benefit in Diabetic Macular Edema from AKB-9778 Tie2 Activation Combined with Vascular Endothelial Growth Factor Suppression. ". Ophthalmology. 2016. PMID 27236272.
  • "Calmodulin Mediates Ca2+-Dependent Inhibition of Tie2 Signaling and Acts as a Developmental Brake During Embryonic Angiogenesis. ". Arterioscler Thromb Vasc Biol. 2016. PMID 27199448.
  • "Blue Rubber Bleb Nevus (BRBN) Syndrome Is Caused by Somatic TEK (TIE2) Mutations. ". J Invest Dermatol. 2017. PMID 27519652.
  • "Systematic analysis of circulating soluble angiogenesis-associated proteins in ICON7 identifies Tie2 as a biomarker of vascular progression on bevacizumab. ". Br J Cancer. 2016. PMID 27351218.
  • "Tie2 Expressing Monocytes in the Spleen of Patients with Primary Myelofibrosis.". PLoS One. 2016. PMID 27281335.

Cyfeiriadau[golygu | golygu cod y dudalen]

  1. 1.0 1.1 1.2 GRCm38: Ensembl release 89: ENSMUSG00000006386 - Ensembl, May 2017
  2. "Human PubMed Reference:".
  3. "Mouse PubMed Reference:".
  4. TEK - Cronfa NCBI