TDRD3

TDRD3
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1WJI, 2LTO, 3PMT, 3PNW, 3S6W
Dynodwyr
Cyfenwau	TDRD3, tudor domain containing 3
Dynodwyr allanol	OMIM: 614392 HomoloGene: 12771 GeneCards: TDRD3
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • methylated histone binding • GO:0001105 transcription coactivator activity • chromatin binding • GO:0001948, GO:0016582 protein binding • RNA binding Cydrannau o'r gell • cytoplasm • exon-exon junction complex • cnewyllyn cell • nucleoplasm • Golgi apparatus • cytosol Prosesau biolegol • regulation of nucleic acid-templated transcription • GO:0031497, GO:0006336, GO:0034724, GO:0001301, GO:0007580, GO:0034652, GO:0010847 chromatin organization • positive regulation of nucleic acid-templated transcription Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	81550	n/a
Ensembl	ENSG00000083544	n/a
UniProt	Q9H7E2	n/a
RefSeq (mRNA)	NM_001146070 NM_001146071 NM_030794	n/a
RefSeq (protein)	NP_001139542 NP_001139543 NP_110421	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn TDRD3 yw TDRD3 a elwir hefyd yn Tudor domain containing 3 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 13, band 13q21.2.

Llyfryddiaeth

• "Tdrd3 is a novel stress granule-associated protein interacting with the Fragile-X syndrome protein FMRP. ". Hum Mol Genet. 2008. PMID 18664458.
• "TDRD3 is an effector molecule for arginine-methylated histone marks. ". Mol Cell. 2010. PMID 21172665.
• "RNA topoisomerase is prevalent in all domains of life and associates with polyribosomes in animals. ". Nucleic Acids Res. 2016. PMID 27257063.
• "Arginine methylation of USP9X promotes its interaction with TDRD3 and its anti-apoptotic activities in breast cancer cells. ". Cell Discov. 2017. PMID 28101374.
• "Crystal structure of TDRD3 and methyl-arginine binding characterization of TDRD3, SMN and SPF30.". PLoS One. 2012. PMID 22363433.